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Toll-like receptor-4 expression and oxidative stress in ocular rosacea.
Mol Vis
November 2024
Centre de Recherche des Cordeliers, INSERM, Université Paris Cité, Sorbonne Université, Physiopathology of ocular diseases: Therapeutic innovations, Paris, France.
Purpose: To investigate systemic and ocular toll-like receptor (TLR)-4 expression and its association with oxidative stress markers in ocular rosacea (OR).
Methods: This prospective study included 40 patients with rosacea with ocular involvement and 20 healthy volunteers. Tear break-up time (TBUT), Schirmer test, meibomoscore, and ocular surface disease index (OSDI) scores were estimated for all participants.
Interleukin-17 inhibitors for the management of severe rosacea.
Australas J Dermatol
December 2024
Department of Dermatology, St George Hospital, Sydney, New South Wales, Australia.
Management of 10 Children With Inflammatory Rosacea With Topical Ivermectin.
Pediatr Dermatol
October 2024
Dermatology Clinic, University of Catania, Catania, Italy.
Rosacea diagnosis and treatment in children are challenging, due to its rarity and to the lack of approved pharmacological agents for its treatment in this age group. In this case series, response to treatment with once daily applications of ivermectin (IVM) 1% cream for 12 weeks in 10 children affected by mild to severe inflammatory rosacea was evaluated clinically by Investigator Erythema Severity Assessment (IESA), Investigator Global Assessment of Severity (IGA-S), Investigator Global Assessment score of Global Efficacy (IGA-GE), and instrumentally by dermoscopy and Erythema-Directed Digital Photography (EDDP). Clinical improvement was achieved at the end of treatment compared to baseline (IESA: 2.
View Article and Find Full Text PDFComparative Analysis of the Cutaneous Microbiome in Psoriasis Patients and Healthy Individuals-Insights into Microbial Dysbiosis: Final Results.
Int J Mol Sci
October 2024
Dermatology Department, Carol Davila University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Article Synopsis
Scalp Rosacea Treated with Topical Ivermectin.
Skin Appendage Disord
October 2024
Dermatology Clinic, University of Catania, Catania, Italy.
Article Synopsis
- Scalp rosacea is frequently misdiagnosed and lacks approved treatments, making it a challenge for healthcare professionals.
- A case study of 5 adults with scalp rosacea showed positive results using ivermectin 1% cream applied daily for 12 weeks.
- The findings indicate that assessing the scalp during rosacea evaluations is important and suggest that ivermectin may be an effective treatment option for scalp rosacea.
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