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There is concern that preprint articles will lead to an increase in the amount of scientifically invalid work available. The objectives of this study were to determine the proportion of prevention preprints published within 12 months, the consistency of the effect estimates and conclusions between preprint and published articles, and the reasons for the nonpublication of preprints. Of the 329 prevention preprints that met our eligibility criteria, almost half (48.9%) were published in a peer-reviewed journal within 12 months of being posted. While 16.8% published preprints showed some change in the magnitude of the primary outcome effect estimate, 4.4% were classified as having a major change. The style or wording of the conclusion changed in 42.2%, the content in 3.1%. Preprints on chemoprevention, with a cross-sectional design, and with public and noncommercial funding had the highest probabilities of publication. The main reasons for the nonpublication of preprints were journal rejection or lack of time. The reliability of preprint articles for evidence-based decision-making is questionable. Less than half of the preprint articles on prevention research are published in a peer-reviewed journal within 12 months, and significant changes in effect sizes and/or conclusions are still possible during the peer-review process.
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http://dx.doi.org/10.1038/s41598-023-44291-4 | DOI Listing |
Heliyon
December 2024
Chair of Construction Management, Ethiopian Institute of Architecture Building Construction and City Development (EiABC), Addis Ababa University, Addis Ababa, Ethiopia.
BIM-Enabled Asset Information Modelling (AIM) entails incorporating extensive data, known as big data, into digital platforms for informed decision-making. However, the lack of accurate and reliable data and the immaturity of BIM integration in existing buildings lead to operational phase performance inefficiencies due to inadequate data access. A strategic approach using BIM-enabled AIM is proposed to address these challenges, with the goal of enhancing data accessibility and adequacy for the operational team's performance.
View Article and Find Full Text PDFJ Multidiscip Healthc
December 2024
Clinical Research Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People's Republic of China.
Background: Online health-related misinformation poses a serious threat to public health. As the coronavirus disease 2019 (COVID-19) pandemic aggravated the spread of misinformation regarding COVID-19, relevant research has surged.
Objective: To systematically summarize Chinese and English articles regarding health-related misinformation about COVID-19 on social media and quantitatively describe research progress.
Inarguably, the green fluorescent protein (GFP) family is an exemplary model for protein engineering, accessing a range of unparalleled functions and utility in biology. The first variant to recognize and provide an optical output of chloride in living cells was serendipitously uncovered more than 25 years ago. Since then, researchers have actively expanded the potential of GFP indicators for chloride through site-directed and combinatorial site-saturation mutagenesis, along with chimeragenesis.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
December 2024
Department of Chemical Engineering, Faculty of Engineering, Jazan University, 11451, Jazan, Saudi Arabia.
The environmental burden of tannery wastewater, characterized by high levels of total dissolved solids (TDS) and other contaminants, presents a significant challenge for sustainable water management. This study addresses this issue by developing a novel polyvinyl alcohol (PVA) and polyvinyl chloride (PVC) composite membrane optimized for efficient TDS removal from tannery effluent. The membrane was fabricated using a solution casting technique, with glutaraldehyde employed as a crosslinking agent to enhance mechanical properties and stability.
View Article and Find Full Text PDFThree-Dimensional Polarized Light Imaging (3D-PLI) and Computational Scattered Light Imaging (ComSLI) map dense nerve fibers in brain sections with micrometer resolution using visible light. 3D-PLI reconstructs single fiber orientations, while ComSLI captures multiple directions per pixel, offering deep insights into brain tissue structure. Here, we introduce the Scattering Polarimeter, a high-speed correlative microscope to leverage the strengths of both methods.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!