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Photon manipulation using quantum interference is crucial for understanding the physical meaning of optical phenomena and promoting photonic quantum technologies. Here, two fundamentally optical phenomena, including coherent perfect absorption (CPA) and slow light trapping, are proposed simultaneously in a double-cavity structure with strontium atoms. When two counterpropagating probe fields are injected into the coupled atom-cavity system, we demonstrate that double-cavity-mediated interference assisted by the atomic Zeeman effect can be utilized to control multiple mode splitting in the transmission light.
View Article and Find Full Text PDFBrachytherapy for cervical cancer: from intracavitary to interstitial technique.
Front Oncol
November 2024
Department of Oncology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Cervical cancer is a common malignant tumor of female reproductive system. Radiation therapy is one of the main methods of cervical cancer treatment, of which brachytherapy is an essential and important part of radiation therapy for locally advanced cervical cancer. With the rapid development of imaging technologies such as computed tomography (CT) and magnetic resonance imaging (MRI), brachytherapy for cervical cancer has gradually developed from traditional two-dimensional image-guided technology to three-dimensional image-guided technology.
View Article and Find Full Text PDFNeurosurgical application of olaparib from a thermo-responsive paste potentiates DNA damage to prolong survival in malignant glioma.
Br J Cancer
December 2024
Children's Brain Tumour Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK.
Article Synopsis
- * Study results show that olaparib effectively targets PARP-1 in glioblastoma cells, leading to reduced cell growth and increased apoptosis, particularly when combined with radiation.
- * Findings indicate that delivering olaparib directly to the tumor area, alongside standard treatments like temozolomide or etoposide, significantly improves long-term survival in glioma models.
Dose Contribution to the Regional Lymph-Node Metastases and Point B from Intracavity and Interstitial Hybrid Brachytherapy in Locally Advanced Cervical Cancer.
Cancers (Basel)
June 2024
Department of Radiation Oncology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Purpose: Analyzing dose distributions to regional lymph-node metastases (RLNMs) in locally advanced cervical cancer (LACC) patients undergoing intracavitary and interstitial hybrid brachytherapy (IC/IS).
Methods: Dose distributions of eleven LACC patients with 38 RLNMs, and who received 38 IC/IS sessions were analyzed in EQD, considering RLNM positions and ipsilateral interstitial needles; these RLNMs, excepting the para-aortic region, were classified into four groups.
Results: RLNMs had a median of two ipsilateral interstitial needles per session.
The current state and future perspectives of radiotherapy for cervical cancer.
J Obstet Gynaecol Res
October 2024
Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Radiotherapy is an effective treatment method for cervical cancer and is typically administered as external beam radiotherapy followed by intracavitary brachytherapy. In Japan, center shielding is used in external beam radiotherapy to shorten treatment time and reduce the doses delivered to the rectum or bladder. However, it has several challenges, such as uncertainties in calculating the cumulative dose.
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