AI Article Synopsis
- - A 66-year-old man with recurring cystic macular edema, possibly linked to Lyme disease, initially received treatment but later developed Vitreoretinal Lymphoma (VRL), confirmed through vitrectomy.
- - After the lymphoma diagnosis, he started a multi-drug chemotherapy regimen and showed a positive response to treatment.
- - Two years later, the patient has had no ocular or systemic recurrences, highlighting the need for early diagnostic suspicion in cases that mimic chronic posterior uveitis.
Article Abstract
A 66-year-old man with posterior uveitis and recurrent cystic macular edema related to possible previously treated Lyme disease is presented. Due to the recurrence of macular edema despite systemic and local corticosteroid treatment with intravitreal dexamethasone, biological treatment with Adalimumab was established. During follow-up, the patient developed bilateral subretinal lesions compatible with Vitreoretinal Lymphoma (VRL), so vitrectomy was performed, confirming the diagnosis of large B-cell lymphoma. Treatment with systemic chemotherapy with BRAM-Carmustine, Metrotexate, Ara C, and Rituximab was started with a good answer. Two years later, the patient remains without ocular or systemic recurrences. Vitreoretinal Lymphoma is a rare type of primary central nervous system lymphoma. The diagnosis is frequently delayed due to the nonspecific symptoms, which mimic chronic posterior uveitis, hence the importance with a diagnostic suspicion.
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| http://dx.doi.org/10.1016/j.oftale.2023.10.002 | DOI Listing |
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