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A new isoflavone from the stems of How. | LitMetric
A preliminary screening test was performed to discover new antihyperlipidaemic active compounds from the leguminous plant How. A new compound, derris-isoflavone F (), and derrubone dimethyl ether (), a known synthetic compound of natural origin, were isolated from the stems of alongside eight recognised compounds. To our knowledge, this is the first instance of documenting the identification of compounds - from this plant. The new compound were evaluated for their antihyperlipidemic and antiproliferative properties. Compound evidently reduced the triglyceride (TG) content in oleic acid-treated HepG2 cells, which validated its efficacy as a potential TG-lowering agent.
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