The recent success of generative adversarial networks and variational learning suggests that training a classification network may work well in addressing the classical two-sample problem, which asks to differentiate two densities given finite samples from each one. Network-based methods have the computational advantage that the algorithm scales to large datasets. This paper considers using the classification logit function, which is provided by a trained classification neural network and evaluated on the testing set split of the two datasets, to compute a two-sample statistic. To analyze the approximation and estimation error of the logit function to differentiate near-manifold densities, we introduce a new result of near-manifold integral approximation by neural networks. We then show that the logit function provably differentiates two sub-exponential densities given that the network is sufficiently parametrized, and for on or near manifold densities, the needed network complexity is reduced to only scale with the intrinsic dimensionality. In experiments, the network logit test demonstrates better performance than previous network-based tests using classification accuracy, and also compares favorably to certain kernel maximum mean discrepancy tests on synthetic datasets and hand-written digit datasets.
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http://dx.doi.org/10.1109/tit.2022.3175691 | DOI Listing |
Zhonghua Yi Xue Za Zhi
January 2025
Ningbo Hangzhou Bay Hospital(Ningbo Branch of Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai),Ningbo315336, China.
To develop a predictive model for improvement of ejection fraction 1 year after heart failure with reduced ejection fraction (HFrEF) following acute ST-segment elevation myocardial infarction (STEMI). This nested case-control study included STEMI patients diagnosed with HFrEF from a prospective multicenter multimodality imaging cohort between August 2014 and March 2021. Based on the improvement of left ventricular ejection fraction (LVEF) at baseline and 1-year follow-up, the patients were classified into the heart failure with improved ejection fraction (HFimpEF) group and the persistent HFrEF group.
View Article and Find Full Text PDFBMC Geriatr
January 2025
Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.
Background: Alanine aminotransferase (ALT) is an enzyme crucial for energy and protein metabolism in muscle cells. Despite this, its association with sarcopenia remains inadequately explored. This study aims to investigate the correlation between serum levels of ALT-related indicators (ALT activity, ALT1, ALT2, and ALT1/ALT2 ratio) and sarcopenia measures, as well as to develop a diagnostic model for sarcopenia in older individuals.
View Article and Find Full Text PDFChin Med J (Engl)
January 2025
Department of Pharmacy, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Key Laboratory of Assessment of Clinical Drugs Risk and Individual Application (Beijing Hospital), Beijing 100730, China.
Background: The use of potentially inappropriate medications (PIMs) is a major concern for medication safety as it may entail more harm than potential benefits for older adults. This study aimed to explore the prescribing rate, healthcare utilization, and expenditure of older adults using PIMs in China.
Methods: A cross-sectional analysis was conducted using a national representative database of all medical insurance beneficiaries across China, extracting ambulatory visit records of adults aged 65 years and above between 2015 and 2017.
Quant Imaging Med Surg
January 2025
School of Computer Science and Technology, Changchun University of Science and Technology, Changchun, China.
Background: Accurate segmentation of rib fractures represents a pivotal procedure within surgical interventions. This meticulous process not only mitigates the likelihood of postoperative complications but also facilitates expedited patient recuperation. However, rib fractures in computed tomography (CT) images exhibit an uneven morphology and are not fixed in position, posing difficulties in segmenting fractures.
View Article and Find Full Text PDFFront Public Health
January 2025
Department of Statistics, Bahir Dar University, Bahir Dar, Ethiopia.
Introduction: Childhood vaccinations are crucial in safeguarding children from infectious diseases and are recognized as one of the most cost-effective public health interventions. However, children in East African countries face more than a fifteen-fold increased risk of death from vaccine-preventable diseases compared to those in high-income nations. This study aimed to identify the factors influencing childhood immunization status in East Africa.
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