The effects of chalazion and the excision surgery on the ocular surface.

Heliyon

Department of Ophthalmology, The Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.

Published: September 2023

AI Article Synopsis

  • The study aimed to assess how removing chalazia affects eye health by measuring both patients' symptoms and objective tear film conditions.
  • 52 eyes from 26 patients were analyzed at different time points, showing significant improvements in symptoms and tear film parameters after surgery.
  • Results indicate that chalazion excision can lead to notable enhancements in eye comfort and tear film quality.

Article Abstract

Purpose: To evaluate the effects of chalazion excision on the ocular surface, taking into account the subjective symptoms and the objective parameters of the tear film.

Methods: This prospective, interventional clinical study included 52 eyes from 26 patients with eyelid chalazion who underwent excision of the lesions between March and August 2022. Chalazion excision was performed on the patient's chalazion eye, and the contralateral eye served as the control. The following parameters were investigated both preoperatively and 1 week, 1 month, and 3 months postoperatively: the Ocular Surface Disease Index (OSDI), Schirmer I test, corneal fluorescein stain (CFS), tear meniscus height (TMH), noninvasive first breakup time (NifBUT), noninvasive average breakup time (NiaBUT), bulbar conjunctival redness score, the thickness of the lipid layer, and meibomian gland loss.

Results: Before surgery, the OSDI score of the chalazion eye was significantly higher than the contralateral eye. The bulbar conjunctival redness score ( = 0.043) and the OSDI score ( = 0.004) improved significantly in the first month after surgery. In the third month after surgery, the objective parameters showed significant improvements, including TMH ( = 0.032), NiaBUT ( = 0.028), bulbar conjunctival redness score ( < 0.001), the thickness of the lipid layer ( = 0.021), and meibomian gland loss ( = 0.005).

Conclusions: Our study revealed that chalazion excision can significantly improve the subjective symptoms and the objective tear film parameters of the ocular surface.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559556PMC
http://dx.doi.org/10.1016/j.heliyon.2023.e19971DOI Listing

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