Poly (lactic acid) (PLA) has distinctive characteristics, including biodegradability, biocompatibility, thermal process ability, high transparency and good film-forming ability. However, PLA has some poor properties that limit its wide applicability. These properties include a low crystallization rate, poor thermal stability, and high brittleness. The main objective of this research was to investigate the effect of a modified elastin-collagen (m-ELA-COLL) matrix on the properties of PLA. The ELA-COLL matrix was extracted from broiler skin waste and modified by grafting using lactic acid monomer to facilitate compatibility with PLA. The extracted and modified ELA-COLL matrix was investigated using FTIR, and α-helix and β-sheet structures were confirmed in both cases (pre- and post-modifications). Modified elastin-collagen dispersed Poly (lactic acid) (PLA-m-ELA-COLL) blend films were prepared using the solution casting method and characterized using DSC and UTM. The effect of m-ELA-COLL as a nucleating agent resulted in the degree of crystallinity improvement of 58.8% with 10 wt% m-ELA/COLL loading, and the elongation at break was improved by 161.3% for PLA-40%-m-ELA-COLL with a tensile strength of 33.75 MPa. The results obtained revealed that the biofilms can be considered as a good candidate to be studied further in the packaging industry.
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http://dx.doi.org/10.1016/j.heliyon.2023.e19598 | DOI Listing |
Pharmaceutics
November 2024
Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Guangdong Pharmaceutical University, No. 280 University Town Outer Ring East Road, Guangzhou 510006, China.
Background: Internal ocular diseases, such as macular edema, uveitis, and diabetic macular edema require precise delivery of therapeutic agents to specific regions within the eye. However, the eye's complex anatomical structure and physiological barriers present significant challenges to drug penetration and distribution. Traditional eye drops suffer from low bioavailability primarily due to rapid clearance mechanisms.
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December 2024
Center of Excellence for Research in Engineering Materials (CEREM), Deanship of Scientific Research (DSR), King Saud University, Riyadh 11421, Saudi Arabia.
This study introduces a novel method to enhance the antibacterial functionality of electrospun nanofibrous textiles by integrating silver nanoparticles (AgNPs) into poly (lactic acid) (PLA) fabrics through pre- and post-electrospinning techniques. AgNPs were incorporated into hydrophobic and modified hydrophilic PLA textiles via pre-solution blending and post-solution casting. A PEG-PPG-PEG tri-block copolymer was utilized to enhance hydrophilicity and water stability, while AgNPs served as antibacterial agents.
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December 2024
Department of Engineering, Pegaso Telematic University, 80143 Naples, Italy.
Lactic acid (LA) is a versatile, optically active compound with applications across the food, cosmetics, pharmaceutical, and chemical industries, largely driven by its role in producing biodegradable polylactic acid (PLA). Due to its abundance, lignocellulosic biomass is a promising and sustainable resource for LA production, although media derived from these matrices are often rich in xylose and contain growth inhibitors. This study investigates LA production using a xylose-rich medium derived from DC stalks treated through steam explosion and enzymatic hydrolysis.
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December 2024
Laboratory of Polymer and Colors Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
The present work focuses on the synthesis and characterization of biobased lignin-poly(lactic) acid (PLA) composites. Organosolv lignin, extracted from beechwood, was used as a filler at 0.5, 1.
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December 2024
Japan Advanced Institute of Science and Technology, Graduated School of Advanced Science and Technology, Asahidai, Nomi 923-1292, Ishikawa, Japan.
We studied the rheological properties under both shear and elongational flow and crystallization behaviors after shear history for binary blends of poly(lactic acid) (PLA) and ethylene-vinyl acetate copolymer (EVA) with a slightly lower shear viscosity. EVA was immiscible with PLA and dispersed in droplets in the blend. The addition of EVA significantly reduced the shear viscosity, which is attributed to the interfacial slippage between PLA and EVA.
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