Introduction Cervical cancer and breast cancer are the major causes of mortality among women worldwide, and the burden of cancer incidence is increasing exponentially. The aim of this study was to assess the relationship between knowledge and practice of postreproductive women toward prevention and screening of breast and cervical cancer in Saudi Arabia. Methods A quantitative, descriptive, cross-sectional study was conducted using a convenience sampling method. One hundred and twenty-eight participants completed the online survey. The questionnaire consists of four main sections: sociodemographic data, obstetrical history, knowledge, and practice of breast and cervical cancer. The correlation coefficient and chi-square test were used to analyze the data. Results Nearly 40% of the participants had good knowledge of the risk factors of breast cancer; 80% had good knowledge of early warnings of breast cancer; 66% had fair knowledge of prevention measures of breast cancer; and 68% had good knowledge of prevention measures of breast cancer. Only 23% of participants had poor knowledge of risk factors of cervical cancer, whereas 62% had fair knowledge of early signs and early screening methods of cervical cancer. The majority of the respondents (85%) had good knowledge of prevention measures for cervical cancer; however, less than one-third of the participants (31%) and 39% had poor or fair practice regarding screening and prevention of breast and cervical cancer, respectively. A significant relationship between practice and knowledge was found as well as a significant relationship between practice and educational level as the p-value was less than 0.05. Conclusion Despite having a comprehensive understanding of avoidable malignancies and screening methods, postreproductive women's utilization of breast and cervical cancer examinations was inadequate. Hence, continuous awareness programs are needed to help women modify their habits and early detections.
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http://dx.doi.org/10.7759/cureus.44858 | DOI Listing |
Arch Gynecol Obstet
January 2025
Department of Pathology, Instituto Português de Oncologia do Porto, Rua Dr. António Bernardino de Almeida, 4200-072, Porto, Portugal.
Introduction: Preterm birth remains a global health challenge with significant perinatal morbidity and mortality rates. Despite extensive research, the underlying mechanisms triggering preterm birth remain elusive, needing a deeper understanding of cervical cellular remodelling processes.
Purpose: This study aims to elucidate the cellular mechanisms underlying cervical remodelling in spontaneous preterm labour (PTL) compared to term labour (TL), focusing on the roles of inflammatory cells and fibroblasts.
J Med Virol
January 2025
Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, P. R. China.
Small-cell neuroendocrine cancer (SCNEC) of the uterine cervix is an exceedingly rare, highly aggressive tumor with an extremely poor prognosis. The cellular heterogeneity, origin, and tumorigenesis trajectories of SCNEC of the cervix remain largely unclear. We performed single-cell RNA sequencing and whole-exome sequencing on tumor tissues and adjacent normal cervical tissues from two patients diagnosed with SCNEC of the cervix.
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January 2025
Radiology, Thammasat University, meung, pathumtani, 12000, Thailand.
Objective: To compare iodine density (ID) and contrast-enhanced attenuation value (CEAV) from dual-layer spectral computed tomography (DLSCT) scans of lymphomatous, metastatic squamous cell carcinoma (SCCA), and normal cervical lymph nodes.
Methods: Data including ID and CEAV were retrospectively collected from patients who underwent DLSCT of the neck between January 2020 and August 2023. Results from each group (lymphomatous, metastatic SCCA, and normal) were compared and analyzed using one-way ANOVA and receiver operating characteristic curve.
Prev Med Rep
January 2025
Department of Obstetrics and Gynecology, University of Campinas. Rua Vital Brasil, 80. CEP 13083-888, Campinas, São Paulo, Brazil.
Objective: To review the epidemiological evidence of cervical cancer among Indigenous women living in Latin America.
Methods: We conducted a systematic review of the evidence contained in 10 databases spanning 2003-2019. Two reviewers independently compared papers' titles and abstracts against the inclusionary criteria, and a third reviewer resolved discrepancies.
Almost all cervical cancers are caused by human papillomaviruses (HPVs). In most cases, HPV DNA is integrated into the human genome. We found that tumor-specific, HPV-human DNA junctions are detectable in serum cell-free DNA of a fraction of cervical cancer patients at the time of initial treatment and/or at six months following treatment.
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