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Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of leaf decoction (crude). | LitMetric

AI Article Synopsis

  • - The World Health Organization has recognized diabetes and obesity as rising epidemics, prompting research into natural remedies, including the essence of a specific plant used for these conditions.
  • - The study focused on exploring the effects of commercially available porridge on diabetes and obesity by preparing a traditional extract from S. dulcis plants and conducting phytochemical screening to identify natural compounds.
  • - Molecular docking studies revealed that the identified compounds from the plant showed strong interactions with target proteins related to anti-diabetic and anti-obesity effects, although further research is required to validate these findings.

Article Abstract

Due to their rising prevalence, diabetes and obesity were both classified as epidemics by the World Health Organization.The natural leaf essence of (), is used as herbal remedy for diabetes and obesity worldwide. However, the objective of the current research was to examine the effects of consuming commercially available porridge on both diabetes and obesity. The S. dulcis plants were collected and the essence was prepared in a traditional way. Phytochemical screening was carried out to identify the secondary metabolites present in the essence. The GC-MS analysis was carried out to identify the bioactive compounds present in the extracts. In order to understand the molecular interaction of identified compounds with selected target proteins from anti-diabetic, anti-oxidant, anti-obesity molecular docking studies was carried out. Results of this docking studies confirmed that identified compounds showed the strong interaction with all the selected target protein. Further experimental analysis is needed to confirm this activity.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557454PMC
http://dx.doi.org/10.6026/97320630019238DOI Listing

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