The regenerative medicine has made great breakthrough in the repair of combat trauma, showing broad prospects, while the method of regenerative medicine applied in the early treatment of combat trauma is not yet clear. The early treatment of combat trauma includes strict control of bleeding, a large amount of blood transfusion, alleviation of acidosis, and correction of hypothermia and improvement of coagulation dysfunction, etc. This paper focuses on the bio-engineered blood, research and development of homeostatic materials, control of inflammation/infection, regulation of immunity, protection of important organs, establishment of military medical model, research and development of biosensors and drugs, and preventive application of stem cell bank in regenerative and tissue engineering in defense medicine to summarize the role of regenerative medicine in the early treatment of combat trauma, hoping to improve the overall treatment level of combat trauma.
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http://dx.doi.org/10.3760/cma.j.cn501225-20220419-00147 | DOI Listing |
PLoS One
January 2025
Department of Coaching Education, Faculty of Sport Sciences, Ataturk University, Erzurum, Türkiye.
This study aimed to investigate the attitudes of combat and team sports athletes towards the use, storage, and hygiene conditions of mouthguards, with the goal of understanding disparities in usage and maintenance practices and their implications for oral health. A cross-sectional study was conducted involving 394 athletes (316 combat athletes and 78 team athletes). Participants completed a 28-question survey assessing their knowledge, attitudes, and practices regarding mouthguard use, hygiene, and maintenance.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Division of Acute Care Surgery, Department of Surgery, University of Michigan, Ann Arbor.
Bioact Mater
April 2025
Department of Orthopedic Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China.
Chronic osteomyelitis caused by implant infections is a common complication following orthopedic surgery. Preventing bacterial infection and simultaneously improving bone regeneration are the key for osteomyelitis. Current treatments include systemic antibiotics and multiple surgical interventions, but the strategies available for treatment are limited.
View Article and Find Full Text PDFMil Med
January 2025
Department of Pediatrics, Uniformed Services University, Bethesda, MD 20814, USA.
Introduction: Children are among the most vulnerable populations affected by armed conflicts, yet there is limited data on the preparedness of military medical personnel to care for pediatric combat trauma casualties in austere or large-scale combat operations. This study aimed to assess the confidence, training needs, and resource requirements of military medical providers who have managed pediatric patients during deployment.
Materials And Methods: This IRB-exempt, cross-sectional mixed-methods study used a survey created via a modified Delphi method with input from subject matter experts.
Pharmaceutics
December 2024
School of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing 400054, China.
Traumatic hemorrhage and infection are major causes of mortality in wounds caused by battlefield injuries, hospital procedures, and traffic accidents. Developing a multifunctional nano-drug capable of simultaneously controlling bleeding, preventing infection, and promoting wound healing is critical. This study aimed to design and evaluate a nanoparticle-based solution to address these challenges effectively.
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