Seizing hope: Advancing cell therapy for pharmaco-resistant epilepsy toward the clinic.

Cell Stem Cell

Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK; The Francis Crick Institute, London, UK; Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany. Electronic address:

Published: October 2023

In this issue of Cell Stem Cell, Bershteyn et al. developed a human interneuron cell therapy that reduced spontaneous seizure activity in a mouse model of mesial temporal lobe epilepsy (MTLE). The data presented here support an ongoing phase 1/2 clinical trial for the treatment of pharmaco-resistant epilepsy in patients.

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http://dx.doi.org/10.1016/j.stem.2023.08.006	DOI Listing

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