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Causal Associations Between Sleep Traits and Delirium: A Bidirectional Two-Sample Mendelian Randomization Study.
Nat Sci Sleep
December 2024
Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, People's Republic of China.
Purpose: Numerous studies have identified a correlation between sleep and delirium; however, the causal relationship remains ambiguous. This bidirectional two-sample Mendelian randomization (MR) study was conducted to examine the possible causal relationships between sleep traits and delirium.
Patients And Methods: Utilizing genome-wide association studies (GWAS), we identified ten sleep traits: chronotype, sleep duration, short sleep duration, long sleep duration, daytime napping, daytime sleepiness, insomnia, number of sleep episodes (NSE), sleep efficiency, and rapid eye movement sleep behavior disorder (RBD).
Investigating the outcomes of full thickness skin graft in the reconstruction of concealed penis in children aged 7 to 14 years.
BMC Urol
December 2024
General Surgery Department, Isfahan University of Medical Sciences, Hezar Jarib Avenue, Isfahan, Iran.
Introduction: Concealed penis is a congenital anomaly that affects not only the appearance but also the function of the external genitalia in the male sex. Different surgical methods have been proposed to correct this disorder, including removal of the previous scar, penile shaft, penile trunk skin reconstruction with flap, penile skin fixation in penopubic and penoscrotal angles, and removal of extra pubic fat. In this study, we will discuss the results of definitive surgery in one stage using autogenous skin grafts and examine the details of this technique.
View Article and Find Full Text PDFNo "One-Size-Fits All": chronic "Carryover" diagnoses dilute antibiotic prescribing rates for sinusitis among adults in primary and urgent care settings.
Infect Control Hosp Epidemiol
December 2024
Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA.
International Classification of Diseases, Tenth Revision (ICD-10) billing data used in outpatient stewardship metrics is under-described for acute and chronic sinusitis. We found that different sinusitis ICD-10 definitions impacted antibiotic prescribing rates (APRs). Chronic sinusitis ICD-10s dilute overall sinusitis APR, particularly in primary care settings and should be examined separately.
View Article and Find Full Text PDFModeling Fibrous Tissue in Vascular Fluid-Structure Interaction: A Morphology-Based Pipeline and Biomechanical Significance.
Int J Numer Method Biomed Eng
January 2025
Department of Mechanics and Aerospace Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Modeling fibrous tissue for vascular fluid-structure interaction analysis poses significant challenges due to the lack of effective tools for preparing simulation data from medical images. This limitation hinders the physiologically realistic modeling of vasculature and its use in clinical settings. Leveraging an established lumen modeling strategy, we propose a comprehensive pipeline for generating thick-walled artery models.
View Article and Find Full Text PDFThe Association between Sociodemographic Factors and Delays to Minimally Invasive Surgery for Stage IA-IIIA Non-Small Cell Lung Cancer.
Ann Thorac Surg
December 2024
University of Colorado, Department of Surgery, Division of Cardiothoracic Surgery, Aurora, CO.
Background: Surgical resection is the gold standard treatment for early-stage non-small cell lung cancer (NSCLC). Prior studies have found that delayed treatment carries risk of disease progression. However, factors that predict delay to surgery are relatively understudied.
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