Investigating Skin Rashes Associated With Pantoprazole Medication: Causes and Clinical Implications.

Cureus

Department of Medical Education, Dubai Academic Health Corporation, Dubai, ARE.

Published: September 2023

AI Article Synopsis

  • Pantoprazole is a proton-pump inhibitor used for gastroesophageal disorders and as a preventive measure against stress ulcers and gastrointestinal bleeding in hospitalized patients.
  • Hypersensitivity reactions to pantoprazole have been reported, but the extent of these reactions is not well understood, highlighting the need for more research in this area.
  • A case study is presented of a 35-year-old male with no significant allergy history who developed an itchy skin rash a week after starting pantoprazole, with no other symptoms reported.

Article Abstract

Pantoprazole is a proton-pump inhibitor mainly used in treating various gastroesophageal disorders and frequently as prophylaxis for stress ulcers and gastrointestinal bleeding in most patients admitted for in-hospital management. Hypersensitivity reactions to this medication have been reported, although the exact incidence and prevalence are unknown. Further studies on proton-pump inhibitor allergic reactions should be conducted to enable physicians to safely select and prescribe an alternative type of medication within the same drug class, confidently avoiding the allergenic molecular compound that the patient reacted to previously. We present a case of a 35-year-old male postoperative bariatric patient with no significant allergy history who developed an allergic skin rash a week after being discharged on pantoprazole 40 mg. His rash was itchy and distributed mainly over the torso and lower limbs, without any additional respiratory or gastrointestinal symptoms.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548015PMC
http://dx.doi.org/10.7759/cureus.44623DOI Listing

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