Bi-HPDO3A as a novel contrast agent for X-ray computed tomography.

Sci Rep

Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Centre, University of Torino, Via Nizza 52, 10126, Turin, Italy.

Published: October 2023

AI Article Synopsis

  • - A new CT imaging agent made from bismuth was developed using a straightforward synthesis method.
  • - Researchers tested the agent for stability, toxicity, and performance in CT imaging.
  • - In vivo imaging was conducted with various doses, and the effectiveness of the 1.2 mmol/kg dose was compared to the established CT agent, iopamidol, at the same dose.

Article Abstract

A new bismuth-based CT agent was synthesized through a facile synthesis strategy. The in vitro stability, toxicity and CT performance were evaluated. The in vivo imaging performance was investigated using three different doses (0.5, 1.2 and 5 mmol/kg) and the result obtained at 1.2 mmol/kg was compared with the clinically approved CT agent iopamidol at the same dosage.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556142PMC
http://dx.doi.org/10.1038/s41598-023-43031-yDOI Listing

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Bi-HPDO3A as a novel contrast agent for X-ray computed tomography.

Sci Rep

October 2023

Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Centre, University of Torino, Via Nizza 52, 10126, Turin, Italy.

Article Synopsis
  • - A new CT imaging agent made from bismuth was developed using a straightforward synthesis method.
  • - Researchers tested the agent for stability, toxicity, and performance in CT imaging.
  • - In vivo imaging was conducted with various doses, and the effectiveness of the 1.2 mmol/kg dose was compared to the established CT agent, iopamidol, at the same dose.
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