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Central myelin dysfunction bridges obesity and neurological diseases. | LitMetric

Central myelin dysfunction bridges obesity and neurological diseases.

Trends Endocrinol Metab

Laboratory of Neurovascular Control of Homeostasis, Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA; Wu Tsai Institute for Mind and Brain, Yale University, New Haven, CT, USA. Electronic address:

Published: January 2024

The central nervous system (CNS) relies on myelin for proper functioning. Myelin remodeling is a risk factor for neurometabolic and endocrine malfunction, resulting in cognitive decline and heightened susceptibility to neurological diseases. The plasticity of myelin upon nutrient shifts may lead to dietary and hormonal interventions for preventing and treating neural complications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10840937PMC
http://dx.doi.org/10.1016/j.tem.2023.09.004DOI Listing

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