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Alzheimers Dement
December 2024
University of California, Davis School of Medicine, Sacramento, CA, USA.
Background: Previous research demonstrates that stress and trauma are associated with poor health and increased dementia risk, but this is mostly based on studies of non-Hispanic Whites. This descriptive analysis delineated the war-related adversity and trauma in participants of the Vietnamese Insights into Cognitive Aging Program (VIP) study, a new cohort of cognitive aging in Vietnamese individuals in Northern California.
Method: VIP is a longitudinal study of 548 Vietnamese Americans aged 65+ years living in Northern California who are seen annually at either research site for three years.
Background: Identifying language variation in healthy aging speakers is important for understanding normal cognitive aging. Setting a baseline of normal aging languages in the first place is necessary for the evaluation of language performances of old adults. Lexical concreteness, a well-studied psycholinguistic parameter, has been used to detect semantic memory-related deficits.
View Article and Find Full Text PDFDeveloping Topics.
Alzheimers Dement
December 2024
Alzheimer's Clinical Trial Consortium, Boston, MA, USA.
Background: Amyloid deposition occurs during the preclinical stages of Alzheimer's disease (AD) a decade or more before clinical symptoms emerge. We leveraged blood transcriptomics and positron emission tomography (PET) measures of amyloidosis to identify cell types and gene networks in the blood that relate to amyloid burden in the brain.
Method: Whole blood RNA sequencing and amyloid PET data were leveraged from 1771 participants (62% females, mean age 71, 32% amyloid+) in the Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Study.
Technology and Dementia Preconference.
Alzheimers Dement
December 2024
National University of Singapore, Singapore, Singapore.
Background: Identifying language variation in healthy aging speakers is important for understanding normal cognitive aging. Setting a baseline of normal aging languages in the first place is necessary for the evaluation of language performances of old adults. Lexical concreteness, a well-studied psycholinguistic parameter, has been used to detect semantic memory-related deficits.
View Article and Find Full Text PDFUltrafast MRI for Pediatric Brain Assessment in Routine Clinical Practice.
Korean J Radiol
January 2025
Department of Radiology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Objective: To assess the feasibility of ultrafast brain magnetic resonance imaging (MRI) in pediatric patients.
Materials And Methods: We retrospectively reviewed 194 pediatric patients aged 0 to 19 years (median 10.2 years) who underwent both ultrafast and conventional brain MRI between May 2019 and August 2020.
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