Background: Aortic dissection is a lethal medical diagnosis associated with high morbidity and mortality. Currently published studies have noted a rising incidence of aortic dissection globally as well as a downward trend in mortality secondary to aortic dissection. There remains no nationally available study here in Aotearoa New Zealand looking into the incidence and mortality of aortic dissection.
Method: A retrospective observational study was performed using data extracted from the Manatū Hauora - Ministry of Health National Minimum Dataset (NMDS) from 1 July 2001 to 30 June 2021. Diagnosis of aortic dissection was based on the ICD-10 version 2 code for aortic dissection (I7100). Population-based statistics were obtained from Statistics New Zealand.
Result: A total of 4,737 patients were included in the study over the 20-year period. The incidence rate of aortic dissection in Aotearoa New Zealand is rising and the current median incidence rate is 4.99 per 100,000 per annum. The mortality rate from aortic dissection is slowly decreasing in Aotearoa New Zealand and the current median mortality rate is 2.19 per 100,000 per annum.
Conclusion: There appears to be a rise in the incidence of aortic dissection in Aotearoa New Zealand and a decrease in the mortality rate.
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http://dx.doi.org/10.26635/6965.6207 | DOI Listing |
Cureus
December 2024
Internal Medicine, Hospital de Braga, Braga, PRT.
Aortic dissection is a life-threatening vascular emergency associated with high morbidity and mortality. Clinical manifestations might include severe chest pain to neurological deficits, depending on the arterial segments involved. Extensive dissections involving multiple aortic segments and branch vessel occlusions, such as the carotid arteries, are rare and pose unique diagnostic and therapeutic challenges.
View Article and Find Full Text PDFCureus
December 2024
Emergency, Hospital de Braga, Braga, PRT.
Pericardial effusion refers to the accumulation of fluid within the pericardial sac, the double-layered membrane surrounding the heart. It can be caused by various medical conditions and may lead to serious complications if not diagnosed and managed promptly. Point-of-care ultrasound (POCUS) has emerged as a valuable tool in the clinical evaluation of pericardial effusions, offering real-time visualization and aiding in the assessment of its size, characteristics, and potential hemodynamic impact.
View Article and Find Full Text PDFJ Vasc Surg Cases Innov Tech
April 2025
Division of Vascular Surgery, London Health Sciences Center, University of Western Ontario, London, Ontario, Canada.
Despite advancements in surgical techniques and critical care, managing complications of type A and B aortic dissections remains challenging. Common morbidities include paraplegia, renal failure, stroke, and intestinal ischemia. Risks are especially high in extensive repairs, such as Crawford extent II thoracoabdominal aortic aneurysms, and in older patients or those with heart failure, poor pulmonary function, or renal disease.
View Article and Find Full Text PDFArterioscler Thromb Vasc Biol
January 2025
Department of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan. (H. Yagi, H.A., Q.L., A.S.-K., M.U., H.K., R.M., A.S., S.O., H.T., Norifumi Takeda, I.K.).
Background: Marfan syndrome (MFS) is an inherited disorder caused by mutations in the gene encoding fibrillin-1, a matrix component of extracellular microfibrils. The main cause of morbidity and mortality in MFS is thoracic aortic aneurysm and dissection, but the underlying mechanisms remain undetermined.
Methods: To elucidate the role of endothelial XOR (xanthine oxidoreductase)-derived reactive oxygen species in aortic aneurysm progression, we inhibited in vivo function of XOR either by endothelial cell (EC)-specific disruption of the gene or by systemic administration of an XOR inhibitor febuxostat in MFS mice harboring the missense mutation p.
Res Pract Thromb Haemost
January 2025
Department of Emergency and Critical Care Medicine, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Background: Acute aortic dissection is a life-threatening cardiovascular emergency with high mortality rates. Disseminated intravascular coagulation (DIC) is a critical complication in patients with acute aortic dissection; however, its incidence and impact on outcomes remain inconclusive.
Objectives: This study aimed to evaluate DIC prevalence and prognosis in patients with aortic dissection.
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