The exposure of humans and animals to environmental compounds is rarely restricted to a single chemical. Cadmium (Cd) and lead (Pb) are two heavy metals known to be the most toxic. Deleterious effects of each metal alone are well documented. Unfortunately, very few studies were conducted to determine their combined effect. Four groups of Wistar rats were treated intravenously for 15 days. The control group received physiological saline solution; groups 2 and 3 were treated with Cd chloride and lead acetate, respectively ; and the treatment group 4 received a combined treatment of Cd and Pb . A significant decrease was recorded for hematological parameters , with an increase in white blood cells and an inhibition in -ALAD level. Cell injury in the livers and kidneys was clearly shown by the significant elevation of the biochemical markers. Cd and Pb induced oxidative stress and had adverse health effects at lower exposure levels than previously thought.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/09603123.2023.2265310 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Conservative mechanism through various rapeseed ( L.) varieties respond to heavy metal (Cadmium, Lead, Arsenic) stress.
Front Plant Sci
January 2025
College of Agriculture, Agricultural University of Hunan, Changsha, China.
Introduction: Heavy metal soil pollution is a global issue that can be efficiently tackled through the process of phytoremediation. The use of rapeseed in the phytoremediation of heavy metal-contaminated agricultural land shows great potential. Nevertheless, its ability to tolerate heavy metal stress at the molecular level remains unclear.
View Article and Find Full Text PDFMonitoring and Assessment of Heavy Metal Concentrations in Two Black Fish Species, Capoeta saadii (Heckel, 1847) and Capoeta trutta (Heckel, 1843), in Western Iran.
Biol Trace Elem Res
January 2025
Department of Biology, Faculty of Science, Arak University, Arak, 384817758, Iran.
Contamination of aquatic ecosystems with heavy metals poses a significant global issue due to its hazardous effects and persistent accumulation in living organisms. This study analyzed 51 fish samples from two species of Black Fish, Capoeta saadii and Capoeta trutta, collected from Iran's Khorramroud River during the summer and fall of 2022 to assess heavy metal accumulation in their gill, liver, and muscle tissues. After biometry, the studied tissues of each fish were isolated to measure the concentration of heavy metals (cadmium (Cd), zinc (Zn), chromium (Cr), lead (Pb), copper (Cu), and nickel (Ni)).
View Article and Find Full Text PDFA short review on polysaccharide-based nanocomposite adsorbents for separation and biomedical applications.
Int J Biol Macromol
January 2025
Department of Chemical Engineering, Arak University, Arak, Iran. Electronic address:
Polysaccharides such as chitosan, alginate, cellulose, and carrageenan have emerged as promising adsorbents due to their biodegradability, abundant availability, and diverse chemical functionality. These biopolymers exhibit promising performance for adsorption of a wide range of pollutants including heavy metals (e.g.
View Article and Find Full Text PDFHealth risk assessment of dietary cadmium exposure based on cadmium bioavailability in food: Opportunities and challenges.
J Hazard Mater
January 2025
Institute of Soil and Water Resources and Environmental Science, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China. Electronic address:
Long-term exposure to Cd through contaminated food can lead to multiple adverse health effects on humans. Although previous studies have covered global food Cd concentrations and dietary Cd exposures across different populations, there are increasing concerns regarding the adequacy of current food Cd safety standards to protect populations from adverse health effects. Moreover, incorporation of Cd relative bioavailability (Cd-RBA) in foods improves the accuracy of health risk assessment.
View Article and Find Full Text PDFOrganic acid release and microbial community assembly driven by phosphate-solubilizing bacteria enhance Pb, Cd, and As immobilization in soils remediated with iron-doped hydroxyapatite.
J Hazard Mater
January 2025
School of Metallurgy and Environment, Central South University, Changsha 410083, PR China. Electronic address:
Although iron-doped hydroxyapatite (Fe-HAP) and its composites have been reported to immobilize arsenic (As), lead (Pb), and cadmium (Cd), its practical application is limited by the inefficient release of iron and phosphate. In this study, Ochrobactrum anthropic, a phosphate-solubilizing bacterium isolated from a lead-zinc smelting site, was employed to enhance multi-heavy metal immobilization in Fe-HAP-amended soils. O.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!