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The oral microbiota: new insight into intracranial aneurysms.
Ann Med
December 2025
Department of Neurointervention, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Background: Intracranial aneurysms (IAs) are a significant clinical concern, with detection rates increasing due to advances in imaging technologies. However, precise mechanisms underlying their pathophysiology remain incompletely understood. Recent evidence suggests a pivotal role of oral microbiota dysbiosis, particularly periodontal pathogens, in systemic inflammation that may contribute to IA development and rupture.
View Article and Find Full Text PDFIncidence and Risk Factors of Peri-Implantitis Over Time-A Prospective Cohort Study.
J Periodontal Res
January 2025
Section of Periodontology, Faculty of Odontology, University Complutense, Madrid, Spain.
Aim: This prospective cohort study aimed to evaluate the incidence and risk/protective factors of peri-implantitis over time.
Methods: A university-representative cohort was evaluated at baseline and after a mean follow-up time of 3.9 years.
The Prevalence of Alveolar Ridge Defects According to Seibert's Classification: A Cross-Sectional Study.
Cureus
December 2024
Prosthodontics, SRM Kattankulathur Dental College and Hospital, SRM Institute of Science and Technology, Chengalpattu, IND.
Background and objective Alveolar ridge defects in partially edentulous patients present significant challenges in prosthodontic treatment planning. Seibert's classification system provides a structured approach to categorizing these defects based on the buccolingual and apico-coronal dimensions of the ridge. Accurate classification is crucial for determining appropriate treatment strategies for implant placement, fixed prosthesis, or tissue augmentation.
View Article and Find Full Text PDFPlatelet-rich fibrin obtained from different protocols affects the formation of the multispecies subgingival biofilm associated with periodontitis.
J Oral Microbiol
January 2025
Department of Biosciences; Piracicaba School of Dentistry, University of Campinas, Piracicaba, Brazil.
Background: The aim of this article is to evaluate the effect of different portions of Platelet Rich Fibrin (PRF) membranes and liquid-PRF, prepared by two distinct protocols/centrifuges each, on the multispecies subgingival biofilm.
Materials And Methods: PRF membranes and liquid-PRF were prepared using two protocols: centrifuge 1 uses fixed acceleration while centrifuge 2, progressive acceleration. PRF samples were introduced into device concurrently with 33-species bacterial inoculum.
Microbiome and Inflammatory Biomarkers Associated With Palatal Wound Healing.
J Periodontal Res
January 2025
College of Dentistry, University of Kentucky, Lexington, Kentucky, USA.
Aim: The clinical outcomes of a variety of surgical procedures highly depend on tissue repair and show high variability among patients. There is a gap in the literature on how the host inflammatory response, the microbiome, and the interplay between them can influence oral mucosa healing. In this pilot study, we aimed to evaluate the microbiome and biomarkers profiles in patients who had desired versus undesired wound healing in the palatal mucosa.
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