Azetidine is a prevalent structural motif found in various biologically active compounds. In this research paper, we report La(OTf)-catalyzed intramolecular regioselective aminolysis of -3,4-epoxy amines to afford azetidines. This reaction proceeded in high yields even in the presence of acid-sensitive and Lewis basic functional groups.
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| http://dx.doi.org/10.3389/fchem.2023.1251299 | DOI Listing |
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