A new tetrahydroimidazopyridine named butyl (5,6,7,8)-5,6,7,8-tetrahydro-6,7,8-trihydroxy-5-(hydroxymethyl)imidazo[1,2-]pyridine-2-carboxylate(), together with eight known compounds (-), were isolated from the fermentation broth of a marine-derived fungus sp. YK-03. Their chemical structures were elucidated by extensive analysis of one-dimensional and two-dimensional NMR spectroscopy, HR-ESIMS and optical rotation. Among these compounds, compound represented a rare tetrahydroimidazopyridine, and compounds - were isolated from the species for the first time. A plausible biosynthetic pathway for compound was proposed.
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| http://dx.doi.org/10.1080/14786419.2023.2262720 | DOI Listing |
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A rare tetrahydroimidazopyridine from the marine-derived fungus sp. YK-03.
Nat Prod Res
October 2023
Department of Medicinal Chemistry and Natural Medicine Chemistry, College of Pharmacy, Harbin Medical University, Harbin, PR China.
A new tetrahydroimidazopyridine named butyl (5,6,7,8)-5,6,7,8-tetrahydro-6,7,8-trihydroxy-5-(hydroxymethyl)imidazo[1,2-]pyridine-2-carboxylate(), together with eight known compounds (-), were isolated from the fermentation broth of a marine-derived fungus sp. YK-03. Their chemical structures were elucidated by extensive analysis of one-dimensional and two-dimensional NMR spectroscopy, HR-ESIMS and optical rotation.
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