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[Extracorporeal organ support as a bridging strategy to enable organ donation-a case report with literature review].
Med Klin Intensivmed Notfmed
January 2025
Klinik für Neurologie und Neurophysiologie, Universitätsklinikum Freiburg, Breisacher Str. 64, 79106, Freiburg, Deutschland.
We report the case of a young patient with severe hypoxic brain injury after cardiopulmonary resuscitation, resulting in brain death/death by neurologic criteria (BD/DNC). Consistent with the patient's expressed wishes, treatment was sustained to facilitate organ donation. However, in the context of a severe post-resuscitation syndrome and physiological disturbances resulting from BD/DNC, refractory circulatory shock ensued.
View Article and Find Full Text PDFHistological Features and Gene Expression Profiling in Lung Transplantation From Donation After Circulatory Death.
Arch Bronconeumol
January 2025
Department of Thoracic Surgery and Lung Transplantation, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; Surgery Department, Medical School, Universidad Autónoma de Madrid (UAM), IDIPHISA, Madrid, Spain.
Challenges and opportunities in organ donation after circulatory death.
J Intern Med
January 2025
Division of Transplantation Surgery, CLINTEC, Karolinska Institutet, Stockholm, Sweden.
In recent years, there has been resurgence in donation after circulatory death (DCD). Despite that, the number of organs transplanted from these donors remains low due to concerns about their function and a lack of an objective assessment at the time of donation. This overview examines the current DCD practices and the classification modifications to accommodate regional perspectives.
View Article and Find Full Text PDFThe 2024 American Association for Thoracic Surgery expert consensus document: Current standards in donor lung procurement and preservation.
J Thorac Cardiovasc Surg
February 2025
Division of Thoracic Surgery, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Background: Donor lung procurement and preservation is critical for lung transplantation success. Unfortunately, the large variability in techniques impacts organ utilization rates and transplantation outcomes. Compounding this variation, recent developments in cold static preservation and new technological advances with machine perfusion have increased the complexity of the procedure.
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