Background: The postacute COVID-19 syndrome (PACS) can be addressed with multidisciplinary approaches, including professional support and digital interventions.
Objective: This research aimed to test whether patients who received a health care facilitation program including medical internet support from human personal pilots and digital interventions (intervention group [IG] and active control group [ACG]) would experience fewer symptoms and have higher work ability and social participation than an untreated comparison group (CompG). The second objective was to compare the impact of a diagnostic assessment and digital interventions tailored to patients' personal capacity (IG) with that of only personal support and digital interventions targeting the main symptoms (ACG).
Methods: In total, 1020 patients with PACS were recruited. Using a randomized controlled trial design between the IG and the ACG, as well as propensity score matching to include the CompG, analyses were run with logistic regression and hierarchical-linear models.
Results: Symptoms decreased significantly in all groups over time (βT1-T2=0.13, t=5.67, P<.001; βT2-T4=0.06, t=2.83, P=.01), with a main effect of the group (β=-.15, t=-2.65, P=.01) and a more pronounced effect in the IG and ACG compared to the CompG (between groups: βT1-T2=0.14, t=4.31, P<.001; βT2-T4=0.14, t=4.57, P<.001). Work ability and social participation were lower in the CompG, but there was no significant interaction effect. There were no group differences between the IG and the ACG.
Conclusions: Empowerment through personal pilots and digital interventions reduces symptoms but does not increase work ability and social participation. More longitudinal research is needed to evaluate the effects of a diagnostic assessment. Social support and digital interventions should be incorporated to facilitate health care interventions for PACS.
Trial Registration: ClinicalTrials.gov NCT05238415; https://classic.clinicaltrials.gov/ct2/show/NCT05238415.
International Registered Report Identifier (irrid): RR2-10.1186/s12879-022-07584-z.
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http://dx.doi.org/10.2196/49342 | DOI Listing |
Rev Sci Instrum
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School of Electronic Engineering, Heilongjiang University, Harbin, HeiLongJiang 150080, China.
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Maxillo-Facial Surgery Department, Beaujon University Hospital, Clichy, France.
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Anal Methods
January 2025
Department of Fundamental Chemistry, LIA3 - Applied Analytical Instrumentation Laboratory, Federal University of Pernambuco, Av. Jornalista Anibal Fernandes, s/n, Cidade Universitária, Recife, PE, 50740-560, Brazil.
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View Article and Find Full Text PDFTuberk Toraks
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Department of Thoracic Surgery, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Lung cancers associated with cystic airspaces (LCCAs) are a rare and relatively novel concept analyzed in various case reports and retrospective studies. In this review, it was our aim to investigate the morphologic, imaging, and clinicopathologic characteristics of this entity, as well as its natural course in light of the current literature. Literature search including the years 2000-2022 was conducted in PubMed.
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