Background: Temporary conductive hearing loss due to vernix accumulation in the external ear canal may lead to a false-positive result in newborn hearing screening tests. The aim of this study was to evaluate whether ear examination and intervention may reduce the false-positive rate prior to hospital discharge.
Methods: A case series of 42 newborns who failed initial otoacoustic emissions screening were studied in our institution between May and December 2020.
Results: During the study period, a total of 735 neonates (1470 ears) were screened by otoacoustic emissions in our hospital. Forty-two newborns who failed otoacoustic emissions were included in our study. They constituted 3.9% (n=58 ears) of the total number of ears screened. Forty-four ears (75.9%) passed and 14 ears (24.1%) failed otoacoustic emissions rescreening performed shortly following vernix cleaning. Twelve of the remaining 14 ears passed at 10-day rescreening. The remaining 2 ears presented true bilateral hearing loss. During the study period, the general false-positive rate decreased from 56/735 (7.61%) to 12/735(1.63%) (P < .00001).
Conclusion: Cleaning the vernix of infants who failed otoacoustic emissions prior to hospital discharge lowers the false-positive rate of universal neonatal hearing screening. We may assume that vernix cleaning will reduce significant healthcare workload, costs of unnecessary investigations, as well as parental anxiety.
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http://dx.doi.org/10.5152/iao.2023.22987 | DOI Listing |
Am J Otolaryngol
December 2024
Department of Clinical Laboratory, Wenzhou People's Hospital, Wenzhou Women and Children's Hospital, Zhejiang, China. Electronic address:
Background: The purpose of the research was to examine the prevalence rates of screening for genetics and hearing simultaneously in neonates and provide scientific evidence for the beneficial application of newborn screening in the Southeast China population.
Methods: Between June 2015 and March 2023, 27,843 newborns were enrolled in the study. All participants were screened by otoacoustic emissions at 2 days of age.
J Am Acad Audiol
July 2024
Department of Audiology, Monash Health Melbourne, Victoria, Australia.
Objective: The objectives of the study were to (i) evaluate the effectiveness of wideband absorbance (WBA) at ambient pressure (WBA), tympanic peak pressure (WBA), and 0 daPa (WBA) to identify conductive hearing loss (CHL) in infants and (ii) compare the sensitivity and specificity of the three WBA tests with that of high-frequency tympanometry (HFT) and transient-evoked otoacoustic emissions (TEOAE).
Method: A total of 31 ears with hearing thresholds no greater than 20 dB HL (reference group from 20 infants [mean age: 3.1 weeks]) and 47 ears with CHL from 31 infants (mean age: 3.
Isr Med Assoc J
December 2024
Department of Dermatology, Emek Medical Center, Afula, Israel.
Background: Little is known about audiovestibular function in psoriasis, a chronic systemic inflammatory disease that affects 2% of the world's population.
Objectives: To investigate audiovestibular function in patients with psoriasis.
Methods: In this prospective case-control trial, we enrolled 33 patients with psoriasis and 30 healthy controls.
Front Psychol
December 2024
Department of Speech, Language and Hearing Sciences, Indiana University, Bloomington, IN, United States.
The Test of Basic Auditory Capabilities (TBAC) consists of 19 discrimination and identification tasks selected to study individual differences in audition. In one TBAC study, performance was measured for 340 normal-hearing subjects, but no investigation into possible sex differences was undertaken. That dataset now has been re-analyzed by sex.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
The Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, 117513 Moscow, Russia.
Auditory neuropathy spectrum disorder (ANSD) is often missed by standard hearing tests, accounting for up to 10% of hearing impairments (HI) and commonly linked to variants in 23 genes. We assessed 122 children with HI, including 102 with sensorineural hearing loss (SNHL) and 20 with ANSD. SNHL patients were genotyped for common variants using qPCR, while ANSD patients underwent whole exome sequencing, with variants analyzed across 249 genes.
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