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[Subacute blindness and aseptic meningitis as presenting signs of autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy].
J Fr Ophtalmol
September 2024
Service d'ophtalmologie, hôpital Pontchaillou, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.
[Fibrillary glomerulonephritis].
Rev Med Interne
November 2024
Département de médecine interne et immunologie clinique, hôpital de la Pitié-Salpêtrière, 75013 Paris, France; Centre de référence maladies auto-immunes systémiques rares, Paris, France; Sorbonne université, Paris, France. Electronic address:
Fibrillary glomerulonephritis (FGN) is a glomerular disease described since 1977, with a prevalence in renal biopsies of less than 1%. It presents as renal failure, proteinuria, haematuria and hypertension in middle-aged adults. It is defined histologically, using light microscopy, which reveals organised deposits of fibrils measuring around 20nm, which are negative for Congo red staining.
View Article and Find Full Text PDF[Latest updates on immunotactoid glomerulopathy and fibrillary glomerulonephritis].
Bull Cancer
July 2024
Inserm U1151 « mechanisms and therapeutic strategies of chronic kidney diseases », hôpital Necker, université Paris Cité, service de néphrologie et transplantation rénale, hôpital Necker, Assistance Publique-hôpitaux de Paris, Paris, France. Electronic address:
Various hematologic malignancies can lead to renal complications. The most common of these hemopathies to affect the kidney is multiple myeloma, however an increasing number of kidney diseases are associated with other monoclonal gammopathies. It is recognized that clones in small abundance can be responsible for severe organ damage, thus the concept of monoclonal gammopathy of renal significance (MGRS) has emerged.
View Article and Find Full Text PDF[Cellularity and extracellularity: the multi-fibrillar system: from cytoskeleton to connective tissue].
Ann Chir Plast Esthet
October 2012
Université Paris Sud 11 & Biopark Campus Cancer, 1, mail Pr Georges Mathé, 94807 Villejuif, France.
This brief text aims at illustrating the interactions between connective tissue fibers and cell cytoskeleton fibers. These two networks are connected by molecular bridges at the level of the cell membrane of the cells of the connective and vascular tissues, allowing functional adjustments across the two domains, but also the transduction of forces and tensions into a biochemical alphabet. The signaling between the cell kern and its environment, but equally the other way round, from the environment to the core of the cell, depends on it.
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