The COVID-19 pandemic drastically underscored the lack of proper health surveillance for people with intellectual and developmental disability (IDD) in the USA. This data equity failure resulted in researchers having to rely on nontraditional data sources to develop an understanding of how this population was faring during the pandemic. To begin addressing this data equity concern, in this commentary, we (1) discuss the difficulties in accessing data during the pandemic specifically related to people with IDD; (2) provide guidance regarding how existing data can be used to examine COVID-19 outcomes for people with IDD; and (3) provide recommendations for improving data collection for people with IDD in light of lessons learned during the pandemic. In sum, the data currently available to examine COVID-19 as well as other health outcomes among people with IDD are severely limited, compromising the ability to both understand and address health disparities among this population.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.dhjo.2023.101539 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Content validation of an activity-based therapy tracking tool in a community setting for people living with spinal cord injury or disease using cognitive debriefing interviews.
PLoS One
January 2025
Rehabilitation Sciences Institute, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Background: Activity-based therapy (ABT) has shown promise as a viable therapeutic intervention to promote neurorecovery in people with spinal cord injury/disease (SCI/D). Tools that track the details of ABT sessions may facilitate the collection of data needed to inform best practice guidelines for ABT.
Objective: The purpose of this study was to evaluate the content validity of a prototype ABT tracking tool.
Testing a Family Conflict Intervention for Parents and Typically Developing Adolescent Siblings of Individuals with Intellectual and/or Developmental Disabilities.
Int J Environ Res Public Health
December 2024
Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA.
Parents and typically developing (TD) youth siblings of individuals with intellectual and/or developmental disabilities (IDD) often experience greater caregiving burden, stress, and hardships in family functioning. They are at increased risk of family conflict and youth adjustment problems when TD siblings are adolescents since they need to balance caregiving responsibilities and various changes that naturally occur during adolescence. However, there is a lack of intervention research on parents and TD adolescent siblings that focuses on family conflict and family-wide participation.
View Article and Find Full Text PDFMARCHF8-mediated ubiquitination via TGFBI regulates NF-κB dependent inflammatory responses and ECM degradation in intervertebral disc degeneration.
PLoS One
January 2025
Department of Orthopedics, Shanghai Pudong New Area People's Hospital, Shanghai, China.
Article Synopsis
- The study investigates the role of TGFBI as a key gene in the development of intervertebral disc degeneration (IDD) and how it is regulated by MARCHF8.
- The researchers used advanced gene analysis techniques to identify significant gene modules related to IDD and found that changes in TGFBI levels affect cell behavior, inflammation, and extracellular matrix breakdown.
- Results indicated that MARCHF8 plays a crucial role in regulating TGFBI expression, which impacts NP cell apoptosis and inflammatory responses through the NF-κB signaling pathway.
MANF overexpression ameliorates oxidative stress-induced apoptosis of human nucleus pulposus cells by facilitating mitophagy through promoting MFN2 expression.
Sci Rep
January 2025
Department of Spine Surgery, The First Affiliated Hospital of Xinjiang Medical University, No.137, Liyu Mountain South Road, Urumqi City, 830054, Xinjiang Province, China.
Intervertebral disc degeneration (IDD) is a degenerative condition associated with impaired mitophagy. MANF has been shown to promote mitophagy in murine kidneys; however, its role in IDD remains unexplored. This study aimed to elucidate the mechanism by which MANF influences IDD development through the regulation of mitophagy.
View Article and Find Full Text PDFNanotechnology-Enhanced Pharmacotherapy for Intervertebral Disc Degeneration Treatment.
Int J Nanomedicine
January 2025
Department of Hand Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an Honghui Hospital North District, Xi'an, Shaanxi, 710000, People's Republic of China.
Intervertebral disc degeneration (IDD) is a primary contributor to chronic back pain and disability globally, with current therapeutic approaches often proving inadequate due to the complex nature of its pathophysiology. This review assesses the potential of nanoparticle-driven pharmacotherapies to address the intricate challenges presented by IDD. We initially analyze the primary mechanisms driving IDD, with particular emphasis on mitochondrial dysfunction, oxidative stress, and the inflammatory microenvironment, all of which play pivotal roles in disc degeneration.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!