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Impact on fluid balance of an optimized restrictive strategy targeting non-resuscitative fluids in intensive care patients with septic shock: a single-blind, multicenter, randomized, controlled, pilot study.
Crit Care
December 2024
Division of Anesthesia, Critical Care, Pain and Emergency Medicine, UR‑UM103 IMAGINE, University of Montpellier, Nimes University Hospital, Nîmes, France.
Background: In septic shock, the classic fluid resuscitation strategy can lead to a potentially harmful positive fluid balance. This multicenter, randomized, single-blind, parallel, controlled pilot study assessed the effectiveness of a restrictive fluid strategy aiming to limit daily volume.
Methods: Patients 18-85 years' old admitted to the ICU department of three French hospitals were eligible for inclusion if they had septic shock and were in the first 24 h of vasopressor infusion.
Impact of adolescents' binge drinking on blood chemistry.
Eur J Pediatr
December 2024
Pediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Della Commenda 9, 20122, Milan, Italy.
Article Synopsis
- - The study examined the effects of binge drinking on adolescent blood chemistry, focusing on glucose, sodium, calcium, potassium, and acid-base balance, by analyzing medical records from 173 teenagers treated at a Milan hospital between 2013 and 2023.
- - Results showed that while glucose, sodium, and calcium levels were generally stable, there were significant cases of hypokalemia and an overwhelming presence of acute respiratory acidosis among binge drinkers.
- - The findings indicate that binge drinking in adolescents leads to notable disturbances in acid-base balance and potassium levels, but has little impact on glucose, sodium, and calcium levels.
Diagnostic validity and solute-corrected prevalence for hyponatremia and hypernatremia among 1 813 356 admissions.
Clin Kidney J
December 2024
Division of Nephrology and Endocrinology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Background And Hypothesis: We aimed to evaluate the diagnostic validity of the International Classification of Diseases, 10th Revision (ICD-10) codes for hyponatremia and hypernatremia, using a database containing laboratory data. We also aimed to clarify whether corrections for blood glucose, triglyceride, and total protein may affect the prevalence and the diagnostic validity.
Methods: We retrospectively identified admissions with laboratory values using a Japanese hospital-based database.
Postoperative delirium following total joint arthroplasty: epidemiology, risk factors, and associated complications.
Hip Int
December 2024
Department of Orthopaedics, Brown University, Providence, RI, USA.
Introduction: Postoperative delirium (POD) is a feared complication following major surgery in elderly patients. Further investigation of the risk factors and consequences of POD following total joint arthroplasty is warranted.
Methods: Patients who underwent total knee arthroplasty (TKA) or total hip arthroplasty (THA) were identified using PearlDiver.
Ceasing or gradually reducing incubator humidity after 7 days for extremely preterm infants: a randomised clinical trial.
Eur J Pediatr
December 2024
Grantley Stable Neonatal Unit (GSNU), Royal Brisbane and Women's Hospital, Herston, Brisbane, QLD, Australia.
Unlabelled: The purpose of this study is to compare the effects of two different ways of stopping incubator humidification on episodes of hypothermia, hyperthermia, hyponatraemia, hypernatraemia, or skin injury. The design is a single site, two-armed, parallel, randomised, clinical trial conducted between April 2019 and March 2022. The setting was a quaternary referral and teaching hospital in Queensland, Australia.
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