AI Article Synopsis

  • The study aimed to assess the impact of thyroid health and metabolic disturbances on oxygen levels during pregnancy, emphasizing the importance of predictive parameters for pregnant women.
  • Conducted over four years with 99 women who experienced preterm delivery, the study included various analyses, such as thyroid tests and glucose tolerance tests, to evaluate their health status.
  • Findings indicated that mothers had an average age of about 32, with most deliveries being vaginal; the use of Doppler sonography to monitor blood flow yielded critical insights into the health of both mothers and babies, especially concerning thyroid issues and gestational diabetes.

Article Abstract

Objectives: Ad fontes, the status of the thyroid gland, and metabolic disturbance lead to the alteration of oxygenation. In pregnancy, it is particularly crucial to possess all predictive parameters.

Methods: This cross-sectional study was conducted at the Clinic of Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade, Serbia, between 2017 and 2021 which study included a total of 99 women who had been admitted for preterm delivery and had undergone thyroid analysis, detected Hashimoto thyroiditis, and Oral Glucose Tolerance Test (OGTT) 40 days after delivery and had pathological Homeostatic Model Assessment for Insulin Response (HOMA IR) indices. In the group of urgent patients with preterm delivery, we looked after not only routine Doppler of the umbilical artery, but we measured specific ratios such as the Cerebroplacental ratio (CP).

Results: The mean maternal age was 32.23 ± 5.96 years and the mean gestational age was detected as 35.40 ± 2.39 weeks. The delivery was completed vaginally in 77 women (78%) and surgically in 22 (22%). The Mean APGAR score was 8.44 ± 1.18, the mean birth weight was 2666.87 ± 622.17g and the cases undergoing cesarean section had significantly higher values of pulsatility index (1.85 ± 0.27 vs. 1.34 ± 0.31) and CP (1.22 ± 0.26 vs. 0.47 ± 0.17).

Conclusions: The introduction of Doppler sonography for blood flow assessment helps to form a complete clinical description of the patient, particularly in conditions where oxidative stress became provocative by the thyroid gland antibodies and gestational diabetes in Thyroidology.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562150PMC
http://dx.doi.org/10.1016/j.clinsp.2023.100279DOI Listing

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