AI Article Synopsis
- Percutaneous pericardiocentesis is a procedure used in cases of cardiac tamponade and for diagnosing unclear chronic pericardial effusions, and this study analyzed the patient characteristics and factors affecting in-hospital mortality.
- A total of 247 patients underwent the procedure between 2011 and 2022, with a 5.67% in-hospital mortality rate and 9.72% requiring repeat procedures, predominantly due to iatrogenic causes and neoplastic diseases.
- Key mortality predictors included myocardial infarction-related causes and recurrent cardiogenic shock, highlighting a higher risk in patients with spontaneous tamponade linked to heart attacks.
Article Abstract
Background: Percutaneous pericardiocentesis represents a salvage procedure in case of cardiac tamponade and diagnostic procedure in chronic pericardial effusion of unknown source. The study aimed to analyze the clinical characteristics of patients subject to pericardiocentesis and the predictors of in-hospital mortality.
Methods: The study represents a registry that covered consecutive patients undergoing percutaneous pericardiocentesis from 2011 to 2022 in high-volume tertiary reference center. Electronic health records were queried to obtain demographic and clinical variables. The primary endpoint was in-hospital mortality, while secondary endpoint was the need for recurrent pericardiocentesis.
Results: Out of 132 456 patients hospitalized in the prespecified period, 247 patients were subject to percutaneous pericardiocentesis (53.9% women; median age of 66 years) who underwent 273 procedures. In-hospital death was reported in 14 patients (5.67%), while recurrent pericardiocentesis in 24 patients (9.72%). Iatrogenic cause was the most common etiology (42.5%), followed by neoplastic disease (23.1%) and idiopathic effusion (14.57%). In logistic regression analysis in-hospital mortality was associated with myocardial infarction (MI)-related etiology ( = 0.001) and recurrent/persistent cardiogenic shock ( = 0.001).
Conclusions: Iatrogenic etiology and neoplastic disease seem to be the most common indications for pericardiocentesis, while in-hospital mortality was particularly high in patients with spontaneous tamponade in the course of MI.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537933 | PMC |
| http://dx.doi.org/10.3389/fcvm.2023.1252525 | DOI Listing |
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