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The concentrations of aztreonam in human tissues obtained during surgery were measured after a single 2-g intravenous dose. The average concentration in the skeletal muscle, atrial appendage, lung, sternum, pericardial fluid, endometrium, myometrium, fallopian tube, and ovary varied from 3 to 33 micrograms/g (or microgram/ml). These concentrations significantly exceed the MIC for 90% of strains for most members of the family Enterobacteriaceae.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC180589 | PMC |
| http://dx.doi.org/10.1128/AAC.30.3.505 | DOI Listing |
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