AI Article Synopsis
- - A 27-year-old woman experienced recurring knee pain, and tests showed minimal inflammation but structures similar to fat in her knee joint.
- - Imaging techniques confirmed the presence of high-intensity signals from these fat-like structures, leading to a diagnosis of lipoma arborescens (LA), for which she underwent synovectomy.
- - Pathology revealed cell growth patterns without T-cell involvement and lower cytokine levels compared to rheumatoid arthritis, suggesting more research is needed to understand LA's cause.
Article Abstract
We herein report a 27-year-old woman who presented with recurrent knee pain. Laboratory findings revealed minimal inflammation. Arthrography revealed structures resembling adipose tissues. Magnetic resonance imaging showed a high signal intensity of these structures, leading to the diagnosis of lipoma arborescens (LA). Synovectomy was performed. Pathology revealed adipocyte proliferation and B-cell clusters but no T-cell infiltration. A serum cytokine analysis revealed low levels of interleukin-6 and tumor necrosis factor-α compared with patients with rheumatoid arthritis. The pathogenesis of LA remains unclear, but immunostaining and serum cytokine levels may provide valuable data for future investigations.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11116025 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.2393-23 | DOI Listing |
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