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The edaphic factor and orchids: Gymnadenia conopsea from contrasting geologies in the Central Balkans.
Planta
January 2025
Institute of Botany and Botanical Garden, Faculty of Biology, University of Belgrade, Belgrade, Serbia.
Two different strategies for the distribution of macro- and trace elements can be observed in the terrestrial orchid Gymnadenia conopsea. Most trace elements are not translocated to the above-ground parts, whereas for macro-elements the trend was reversed, with the highest accumulation in the distal parts of the plants. Edaphic stress is one of the main factors affecting plant fitness, but it is still poorly understood, even in rare plants such as orchids.
View Article and Find Full Text PDFComprehensive characterization of tobacco-induced changes in enamel surface topography.
J Oral Biol Craniofac Res
December 2024
Department of Oral Biology and Oral Pathology, Saveetha Dental College and Hopsitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, India.
Introduction: Enamel translucency, essential for the aesthetic appeal of teeth, is primarily determined by its thickness, quality, and refractive index. Several factors, including age, genetics, diet, oral hygiene practices, fluoride exposure, and acidic challenges, can influence enamel translucency. Tobacco use, in particular, leads to significant alterations in enamel appearance by penetrating its micropores, causing yellowing and browning.
View Article and Find Full Text PDFThe interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity.
J Neuroinflammation
January 2025
Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, USA.
The thrombolytic protease tissue plasminogen activator (tPA) is expressed in the CNS, where it regulates diverse functions including neuronal plasticity, neuroinflammation, and blood-brain-barrier integrity. However, its role in different brain regions such as the substantia nigra (SN) is largely unexplored. In this study, we characterize tPA expression, activity, and localization in the SN using a combination of retrograde tracing and β-galactosidase tPA reporter mice.
View Article and Find Full Text PDFGenetic inbreeding load and its individual prediction for milk yield in French dairy sheep.
Genet Sel Evol
January 2025
GenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Castanet-Tolosan, France.
Background: The magnitude of inbreeding depression depends on the recessive burden of the individual, which can be traced back to the hidden (recessive) inbreeding load among ancestors. However, these ancestors carry different alleles at potentially deleterious loci and therefore there is individual variability of this inbreeding load. Estimation of the additive genetic value for inbreeding load is possible using a decomposition of inbreeding in partial inbreeding components due to ancestors.
View Article and Find Full Text PDFEvolution of the RNA alternative decay element into a high-affinity target for the immunomodulatory protein Roquin.
RNA Biol
December 2025
Institute for Molecular Biosciences and Biomolecular Resonance Center (BMRZ), Goethe University Frankfurt, Frankfurt, Germany.
RNA elements play pivotal roles in regulatory processes, e.g. in transcriptional and translational regulation.
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