Microcystin-LR (MC-LR), as a hepatotoxin, can cause liver swelling, hepatitis, and even liver cancer. In this study, MC-LR aptamer (Apt-3) modified graphene oxide (GO) was designed to enrich MC-LR in white jade snail (Achatina fulica) and pond water, followed by matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) analysis. Results indicated that the Apt-3/PEG/GO nanocomposites were highly specific to MC-LR, and the detection limit of MALDI-MS was 0.50 ng/mL. Moreover, the MC-LR can be released from nanocomposites at 75°C, thus, the reuse of Apt-3/PEG/GO is realized. Real sample analysis indicated that the Apt-3/PEG/GO nanocomposites coupled with MALDI-MS were efficient in detecting trace amounts of MC-LR in real samples. With the merits of being low cost, reusable, and easy to besynthesized, this Apt-3/PEG/GO MALDI-MS is expected to be comprehensively applied by anchoring suitable aptamers for different targets.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/elps.202300107 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Combined Graphene Oxide with 2-Methoxyestradiol for Effective Anticancer Therapy in-vitro Model.
Int J Nanomedicine
January 2025
Department of Medical Chemistry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland.
Introduction: This article describes the invention of graphene oxide (GO) or reduced graphene oxide (rGO) functionalised with 2-methoxy estradiol. The presence of polar hydroxyl groups enables the binding of 2-ME to GO/rGO through hydrogen bonds with epoxy and hydroxyl groups located on the surface and carbonyl and carboxyl groups located at the edges of graphene flake sheets.
Methods: The patented method of producing the subject of the invention and the research results regarding its anticancer effectiveness via cytotoxicity in an in vivo model (against A375 melanoma and 143B osteosarcoma cells) are described.
Unconventional Photocapacitor Utilizing Metal-Organic Dye Capable of Operating in Low Intensity Light.
ACS Appl Mater Interfaces
January 2025
Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar 388120, Gujarat, India.
The development of devices capable of storing energy harnessed from photons is on the rise, owing to the increasing global energy demand for smart systems. The majority of reports in this field cover the use of integrated type devices, which houses a separate photovoltaic module and supercapacitor or battery. Herein, we are reporting a photocapacitor with a simple two-electrode design, capable of operating without a conventional electrolyte or metal ions.
View Article and Find Full Text PDFAuNPs/GO/Pt microneedle electrochemical sensor for in situ monitoring of hydrogen peroxide in tomato stems in response to wounding stimulation.
Anal Bioanal Chem
January 2025
School of Life Sciences, Nantong University, 9 Seyuan Road, Nantong, 226019, Jiangsu, China.
Hydrogen peroxide (HO) is a critical signaling molecule with significant roles in various physiological processes in plants. Understanding its regulation through in situ monitoring could offer deeper insights into plant responses and stress mechanisms. In this study, we developed a microneedle electrochemical sensor to monitor HO in situ, offering deeper insights into plant stress responses.
View Article and Find Full Text PDF[Applications and prospects of graphene and its derivatives in bone repair].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
January 2025
Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, P. R. China.
Objective: To summarize the latest research progress of graphene and its derivatives (GDs) in bone repair.
Methods: The relevant research literature at home and abroad in recent years was extensively accessed. The properties of GDs in bone repair materials, including mechanical properties, electrical conductivity, and antibacterial properties, were systematically summarized, and the unique advantages of GDs in material preparation, functionalization, and application, as well as the contributions and challenges to bone tissue engineering, were discussed.
Cerium oxide nanoparticles decorated on graphene oxide nanosheets as battery-type cathode material for supercapacitors.
J Colloid Interface Sci
January 2025
Department of Physics, Malaviya National Institute of Technology Jaipur, Rajasthan 302017 India. Electronic address:
Designing advanced materials that effectively mitigate the poor cycle life of battery-type electrodes with high specific capacities is crucial for next-generation energy storage systems. Herein, graphene oxide-ceria (GO-CeO) nanocomposite synthesized via a facile wet chemical route is explored as cathode for high-performance supercapacitors. The morphological analysis suggests fine ceria (CeO) nanoparticles dispersed over ultrathin graphene oxide (GO) sheets while structural studies reveal face-centered cubic phase of CeO in the nanocomposite.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!