To increase the yield of living cells and their survival, studies were carried out to optimize the method for isolating cardiomyocytes from biopsy specimens excised from the right atrial appendages. It was found that creatine, blebbistatin, and taurine are necessary components of the buffer solution during cardiomyocyte isolation, and that composition of the solutions is a more important factor than their oxygenation.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10517-023-05907-xDOI Listing

Publication Analysis

Top Keywords

biopsy specimens
8
development method
4
method isolation
4
isolation mature
4
mature cardiomyocytes
4
cardiomyocytes human
4
human heart
4
heart biopsy
4
specimens increase
4
increase yield
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!