AI Article Synopsis
- The viable but non-culturable (VBNC) state of pathogenic bacteria is often overlooked but plays a crucial role in recurrent infections and disease spread.
- VBNC allows bacteria to survive various stresses in healthcare settings and inside hosts, acting as a mechanism for long-term persistence.
- New detection methods need to be developed to identify these viable pathogens beyond traditional culture techniques.
Article Abstract
Currently, the viable but non-culturable (VBNC) state is an underappreciated niche for pathogenic bacteria which provides a continuous source for recurrent infections and transmission. We propose the VBNC state to be a global persistence mechanism used by various strains to cope with many stresses it is confronted with in the clinical environment and in the host. This requires a novel strategy to detect viable cells of this pathogen that is not only based on plating assays.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653857 | PMC |
| http://dx.doi.org/10.1128/mbio.02139-23 | DOI Listing |
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