AI Article Synopsis
- Hypertrophic cardiomyopathy is a heart condition that runs in families and can cause problems like irregular heartbeats and heart failure.
- One major issue can happen when blood has trouble flowing out of the heart, making it work harder.
- Doctors can use different treatments like medications and special procedures to help improve the heart's function and make patients feel better.
Article Abstract
Hypertrophic cardiomyopathy is the most common genetic cardiomyopathy. Main complications include the development of arrhythmias and heart failure, and the latter may be triggered by left ventricular outflow tract obstruction. The treatment of left ventricular outflow tract obstruction includes pharmacological therapies (beta-blockers, calcium channel blockers, disopyramide) and septal reduction therapies (alcohol septal ablation, surgical myectomy). Myosin inhibitors represent a new therapeutic opportunity and in recent clinical trials proved effective in symptom relief, improvement of functional capacity and quality of life in patients with obstructive hypertrophic cardiomyopathy. In this narrative review we will summarize the available and under development therapeutic approaches for hypertrophic cardiomyopathy.
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| http://dx.doi.org/10.1714/4100.40979 | DOI Listing |
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