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The Between Lung Cancer and Interstitial Lung Diseases: A Focus on Acute Exacerbation.

J Clin Med

November 2024

Department of Medicine and Surgery, University of Milano-Bicocca, SC Pneumologia, Fondazione IRCCS "San Gerardo dei Tintori", 20900 Monza, Italy.

Patients with interstitial lung disease (ILD) are about five times more likely to develop lung cancer than those without ILD. The presence of ILD in lung cancer patients complicates diagnosis and management, resulting in lower survival rates. Diagnostic and treatment procedures needed for cancer can increase the risk of acute exacerbation (AE), one of the most severe complications for these patients.

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Article Synopsis
  • Biopsy tools are crucial for accurate bronchoscopic diagnoses, and cryobiopsy has gained attention for its effectiveness in identifying thoracic diseases.
  • Cryobiopsy has shown higher diagnostic yields compared to traditional forceps biopsies, thanks to its ability to collect larger tissue samples through freezing.
  • Despite some risk of complications, the improved diagnostic accuracy makes cryobiopsy a valuable method for evaluating conditions related to the lungs and surrounding areas.
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Objective: To present a case series with a long-term follow-up of CT-guided cryoablation procedure for the minimally invasive treatment of symptomatic lumbar facet synovial cyst with a mean follow-up of 38 months (range, 15-55).

Materials And Methods: We present a retrospective, uncontrolled clinical case series in a single institution on patients treated with CT-guided cryoablation for symptomatic lumbar facet joint synovial cyst refractory to or not suitable for imaging-guided rupture procedure. In two cases, patients underwent cryoablation and cyst rupture within a 2-week period.

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Background: Osteoid osteoma is a benign bone tumor with characteristic clinical symptomatology. The selected method for its treatment is percutaneous radiofrequency ablation. However, percutaneous cryoablation is an alternative method with certain advantages.

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Introduction: Shape-sensing Robotic-assisted Bronchoscopy (ssRAB) has emerged as a promising tool for improved performance when sampling pulmonary nodules (PPN). Previous studies suggest that the 1.1 mm cryoprobe is as effective compared to fine needle aspiration (FNA), for different lesions sizes.

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