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Self- versus clinician-collected swabs in anal cancer screening: A clinical trial.
PLoS One
January 2025
Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Background: Risk of anal cancer is high in certain populations and screening involves collection of anal swabs for HPV DNA and/or cytology testing. However, barriers exist, such as the need for an intimate examination, and stigma around HIV status, sexual orientation, and sexual practices. Self-collected anal swabs (SCA) are a proposed alternative to clinician-collected swabs (CCA) to overcome these barriers.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Douglas Mental Health Research Centre, Montreal, QC, Canada.
Background: Synaptic dysfunction is a central pathologic feature of Alzheimer's disease (AD), with synaptic loss even preceding neuronal loss in specific brain regions. In healthy individuals, synaptic function and plasticity are orchestrated through the complex integration of signaling inputs generated by cell surface receptors.
Methods: In this study, we investigate the role of one such receptor, protein tyrosine phosphatase receptor sigma (PTPRS), in the context of Alzheimer's disease.
Bilateral Ovarian Agenesis and Bone Modeling Disease in Pre-puberty Girl With Primary Amenorrhea.
Cureus
December 2024
Department of Obstetrics and Gynecology, Royal Medical Services, Amman, JOR.
Ovarian agenesis (OA) is a rare congenital condition characterized by the absence of one or both ovaries, often associated with chromosomal abnormalities, hormonal imbalances, and structural deformities. The condition is frequently diagnosed in females presenting with primary amenorrhea and delayed sexual development. This case report highlights a unique presentation of bilateral ovarian agenesis in a patient with chromosome X translocation, bone modeling disease, and primary amenorrhea.
View Article and Find Full Text PDFParental effects provide an opportunity for coral resilience following major bleaching events.
PLoS One
January 2025
School of Aquatic and Fishery Sciences, University of Washington, Seattle, WA, United States of America.
Identifying processes that promote coral reef recovery and resilience is crucial as ocean warming becomes more frequent and severe. Sexual reproduction is essential for the replenishment of coral populations and maintenance of genetic diversity; however, the ability for corals to reproduce may be impaired by marine heatwaves that cause coral bleaching. In 2014 and 2015, the Hawaiian Islands experienced coral bleaching with differential bleaching susceptibility in the species Montipora capitata, a dominant reef-building coral in the region.
View Article and Find Full Text PDFThe impact of reproductive health knowledge, reproductive health-promoting behavior, and sexual communication on intention to visit obstetrics and gynecology in unmarried women: a cross-sectional study.
Womens Health Nurs
December 2024
Department of Nursing, Pukyong National University, Busan, Korea.
Purpose: Women are experiencing reproductive health abnormalities at younger ages, and the incidence of cervical cancer in women in their 20s and 30s is increasing. Various factors hinder visits to obstetrics and gynecology. This cross-sectional study aimed to explore how health knowledge, reproductive health-promoting behavior, and sexual communication influenced the degree of intention to visit obstetrics and gynecology in unmarried women.
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