AI Article Synopsis
- Conventional drug discovery is time-consuming and expensive, making it hard to find new treatments for tough diseases.
- Drug repurposing offers a solution by using previously approved medications for new therapeutic applications, ensuring they are safe and effective from prior testing.
- This review focuses on identifying repurposable drugs, particularly in the context of immunotherapy.
Article Abstract
Conventional drug discovery involves significant steps, time, and expenses; therefore, novel methods for drug discovery remain unmet, particularly for patients with intractable diseases. For this purpose, the drug repurposing method has been recently used to search for new therapeutic agents. Repurposed drugs are mostly previously approved drugs, which were carefully tested for their efficacy for other diseases and had their safety for the human body confirmed following careful pre-clinical trials, clinical trials, and post-marketing surveillance. Therefore, using these approved drugs for other diseases that cannot be treated using conventional therapeutic methods could save time and economic costs for testing their clinical applicability. In this review, we have summarized the methods for identifying repurposable drugs focusing on immunotherapy.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536625 | PMC |
| http://dx.doi.org/10.3390/pharmaceutics15092190 | DOI Listing |
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