AI Article Synopsis
- - Since the first African swine fever (ASF) outbreak in South Korea in September 2019, there have been 31 cases on pig farms and nearly 2800 infected wild boars detected by January 2023, indicating a high risk of the virus spreading to domestic pigs.
- - Despite concerns about the pathogenicity of ASFV strains, a previous study found no changes in virulence from 2019 to 2021; this new research aimed to investigate strains from 2022 to early 2023 for possible alterations.
- - The study identified two ASFV strains with potentially reduced pathogenicity, but all pigs inoculated with these strains died 8-10 days later, showing consistent symptoms and lesions, suggesting that
Article Abstract
Since the first African swine fever (ASF) outbreak occurred at a pig farm in South Korea in September 2019, as of 31 January 2023, 31 ASF cases have occurred at pig farms, while 2799 ASF virus (ASFV)-infected wild boars have been identified. The circulation of ASFV in wild boar populations poses a high risk of spillover to pig farms in the country. However, information on the changes in the pathogenicity of Korean ASFV strains from wild boars is not available. Investigating the pathogenicity of ASFV strains from pig farms is the only way to predict their alterations. In a previous study, no changes in the pathogenicity of ASFV strains circulating during 2019-2021 were identified through animal experiments. In this study, we chose two ASFV strains with potentially reduced pathogenicity among ten viruses obtained from pig premises from 2022 to January 2023 and estimated their pathogenicities and pathological characteristics. All the inoculated pigs died 8-10 days post-inoculation after showing pyrexia, depression, anorexia, and recumbency together with the common pathological lesions of enlarged hemorrhagic lymph nodes and splenomegaly with infarction. These results support that the pathogenicity among ASFV isolates in South Korea still remained unchanged during the study period.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534632 | PMC |
| http://dx.doi.org/10.3390/pathogens12091158 | DOI Listing |
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