This paper presents an overview of representative up-to-date research and the authors' own experimental results from tests of wall elements and a horizontally loaded timber-framed modular building. The research has been conducted in connection with the development of timber-based structures in recent years. In the present research, wall elements and modules of timber-frame construction with life-size dimensions were used. So far, these types of structures have mainly been tested in laboratories-especially with regard to anchoring and cyclic loading. An experimental testing was carried out on a natural scale in two stages based on the standard procedure described in EN 594. In the first stage, wall panels were tested. In the second stage, tests were carried out on a complete four-storey building. Dowel fasteners were used to fix the sheathing to the load-bearing wall structures. Additionally, the sheathing was glued to the timber frame of the walls. The same type of wall element was used for the construction of the tested building. Horizontal loads were applied at the height of the top of the walls in both stages. The building loads were applied in a direction perpendicular to the longitudinal axis of the modules. Based on test data, the stiffnesses of the wall panels and the whole building were derived, as well as the type of interaction between the modules and the influence of the walls on the spatial work of the building. On the basis of the conducted studies, both the stiffness of the walls in different configurations and the stiffness of the complete building were determined, as well as the nature of the interaction of neighbouring modules and the influence of wall connections on the 3D working of the building. The results show that the stiffness of the building in the horizontal plane in the direction of the applied load is almost twice as high as the sum of the stiffnesses of the building walls in the same direction.
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http://dx.doi.org/10.3390/ma16186229 | DOI Listing |
BJOG
January 2025
Department of Public Health, Aarhus University, Aarhus, Denmark.
Objective: To build consensus on most important symptoms and related consequences for use in questionnaires to characterise individuals with suspected and confirmed endometriosis in the general population.
Design: A questionnaire of 107 symptoms and related consequences of endometriosis was collaboratively developed by patients, medical doctors and researchers and further assessed in a two-round e-Delphi study. Participants assessed the relevance of the symptoms, and a priori it was decided that 70% was the threshold for inclusion of a symptom.
JMIR Form Res
January 2025
School of Nursing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 5/F, Academic Building, Pokfulam, Hong Kong, China (Hong Kong), 852 39176690.
Background: Breastfeeding is vital for the health and well-being of both mothers and infants, and it is crucial to create supportive environments that promote and maintain breastfeeding practices.
Objective: The objective of this paper was to describe the development of a breastfeeding-friendly app called "bfGPS" (HKU TALIC), which provides comprehensive territory-wide information on breastfeeding facilities in Hong Kong, with the goal of fostering a breastfeeding-friendly community.
Methods: The development of bfGPS can be categorized into three phases, which are (1) planning, prototype development, and preimplementation evaluation; (2) implementation and updates; and (3) usability evaluation.
Org Biomol Chem
January 2025
Key Laboratory of Evolution & Marine Biodiversity (Ministry of Education) and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Dihydronaphthalenes play a crucial role in bioactive natural products and new drug discovery, and efficient and economic strategies to build them are needed. Herein, we disclose a highly efficient method to prepare dihydronaphthalenes a cerium-catalyzed cycloaddition of 1-isochromenes with cinnamic acids. This newly developed method not only features a broad and low-cost substrate scope and mild conditions but also exhibits very high functional group tolerance, including hydroxyl, borate ester and ester group substituents.
View Article and Find Full Text PDFAm J Cancer Res
December 2024
Department of Reproductive Medicine, The First Affiliated Hospital, Jinan University Guangzhou 510000, Guangdong, China.
This study aims to construct and optimize risk prediction models for lymph node metastasis (LNM) in endometrial carcinoma (EC) patients, thus improving the identification of patients at high risk of LNM and further providing accurate support for clinical decision-making. This retrospective analysis included 541 cases of EC treated at The First Affiliated Hospital, Jinan University between January 2017 and January 2022. Various clinical and pathological variables were incorporated, including age, body mass index (BMI), pathological grading, myometrial invasion, lymphovascular space invasion (LVSI), estrogen receptor (ER) and progesterone receptor (PR) levels, and tumor size.
View Article and Find Full Text PDFHeart Rhythm O2
December 2024
Cardiology Department, Bichat Hospital, Paris, France.
Background: Detection of atrial tachyarrhythmias (ATA) on long-term electrocardiogram (ECG) recordings is a prerequisite to reduce ATA-related adverse events. However, the burden of editing massive ECG data is not sustainable. Deep learning (DL) algorithms provide improved performances on resting ECG databases.
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