AI Article Synopsis
- The study analyzed frailty and subjective cognitive decline (SCD) in 1157 non-demented Japanese adults aged 70 and older from 2013 to 2019, using the Kihon Checklist and Subjective Memory Complaints scale.
- Three trajectories for both frailty and SCD were identified: non-progressive, moderate progressive, and rapid progressive, with individuals in the rapid progressive SCD group having a notable overlap with rapid progressive frailty.
- The findings suggest that those with rapid progressive frailty and SCD face an increased risk of depressive symptoms and slow gait speed, indicating a need for interventions that address both cognitive decline and mental health.
Article Abstract
We studied frailty and subjective cognitive decline (SCD) trajectories in older Japanese adults and evaluated the influence of various factors on these trajectories. We analyzed data from 1157 non-demented adults aged 70 and above from 2013 to 2019. Frailty was assessed using the self-administered Kihon Checklist (KCL), a Japanese frailty index. SCD was evaluated using the questionnaire of the Subjective Memory Complaints scale. Through group-based joint trajectory models, we discerned three frailty trajectories: non-progressive ( = 775), moderate progressive ( = 312), and rapid progressive ( = 70); and three SCD trajectories: non-progressive ( = 302), moderate progressive ( = 625), and rapid progressive ( = 230). Individuals in the rapid progressive SCD trajectory had a 32.2% probability of also being in the rapid progressive frailty trajectory. In contrast, those in the non-progressive SCD trajectory had zero probability of being in the rapid progressive frailty trajectory. Both the rapid progressive frailty and SCD groups combined had a higher incidence of depressive symptoms and slow gait speed. Our results have found that frailty and SCD share a similar trajectory in Japanese older adults. Additionally, rapid progressive frailty and SCD were associated with the highest risk of depressive symptoms and slow gait speed. Thus, interventions targeting both frailty and cognitive decline should prioritize mental health enhancement and gait speed improvement.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532373 | PMC |
| http://dx.doi.org/10.3390/jcm12185803 | DOI Listing |
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