A biphasic effect of age on CPAP adherence: a cross-sectional study of 26,343 patients.

Respir Res

Département de Pneumologie, Hôpital Arnaud de Villeneuve, CHRU de Montpellier, Montpellier, France.

Published: September 2023

Background: As the prevalence of OSA increases in older patients, the proportion of elderly patients treated with CPAP is expected to become even higher. We studied CPAP-adherence in a real-life cohort involving a large population of elderly patients with OSA.

Methods: eQUALISAS is a cross-sectional study of CPAP treated OSA patients for at least 4 months who received remote monitoring during 2021. CPAP adherence, device-reported residual AHI (AHI) and 95th percentile non-intentional leaks were software collected during January 2021. Age and sex were also collected.

Results: Data from 26,343 patients including 1656 patients aged [80-85] years and 639 patients aged ≥ 85 years were analysed. Median CPAP adherence increases from 6.3 h (< 50 years) to 7 h (75-80 years) and decreases after this age (p < 0.001). The decrease in CPAP adherence observed after the age of 80 was associated with an increase in the proportion of patients with a CPAP-adherence < 4 h/day (p < 0.001). Proportion of CPAP treated female, patients having AHI mean ≥ 10 events per hour or 95th percentile non-intentional leaks mean over 24 l/min increase with aging of the population. However, for patients over 80 years old, Chi square test showed no association of adherence with gender, AHI and leaks (p > 0.05).

Conclusion: This study demonstrates that adherence gradually increases with age until 80 years. The proportion of non-adherent patients grows with age after 80 years old. No significative relationship was found between adherence after 80 years old and gender, leaks and AHI.

Trial Registration: The study is registered on Health Data Hub platform (No. F20220715144543).

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537927PMC
http://dx.doi.org/10.1186/s12931-023-02543-xDOI Listing

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