In this study, a novel long-lived room-temperature phosphorescent (RTP) carbon dots (P-CDs) with the properties of ultraviolet/visible (UV/Vis) light photoresponsive oxidase-like nanozyme were synthesized from diethylenetriaminepentaacetic acid and through a one-step hydrothermal method. P-CDs were used as a light-driven oxidative-like enzyme for antimicrobial studies. The results showed that under UV/Vis light irradiation, P-CDs could efficiently convert O into O, and the strong oxidizing property of O greatly enhanced the growth inhibition of P-CDs on Gram-positive Staphylococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli). Meanwhile, P-CDs exhibited good photodynamic antifungal properties against Botrytis cinerea (B. cinerea). Then the P-CDs were made into P-CDs/PVA films, which effectively prolonged the preservation period of fruits under photodynamic antibacterial action. The good biocompatibility and efficient photosensitive oxygen activation can make P-CDs a more practically useful oxidase-like nanozyme.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.foodchem.2023.137541 | DOI Listing |
Anal Chem
January 2025
Yunnan Key Laboratory of Modern Separation Analysis and Substance Transformation, College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500, Yunnan Province, P. R. China.
Early and portable detection of pathogenic bacteria is crucial for ensuring food safety, monitoring product quality, and tracing the sources of bacterial infections. Moving beyond traditional plate-culture counting methods, the analysis of active bacterial components offers a rapid means of quantifying bacteria. Here, metal-organic framework (MOF)-derived NiCo-layered double hydroxide nanosheets (LDHs), synthesized via the Kirkendall effect, were employed as highly effective oxidase mimics to generate reactive oxygen species (ROS).
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, China.
The intricacy, diversity, and heterogeneity of cancers make research focus on developing multimodal synergistic therapy strategies. Herein, an oxygen (O) self-feeding peroxisomal lactate oxidase (LOX)-based LOX-Ce6-Mn (LCM) was synthesized using a biomineralization approach, which was used for cascade chemodynamic therapy (CDT)/photodynamic therapy (PDT) combination therapies through dual depletion of lactate (Lac) and reactive oxygen species (ROS) generation. After endocytosis into tumor cells, the endogenous hydrogen peroxide (HO) can be converted to O by the catalase-like (CAT) activity of LCM, which can facilitate the catalytic reaction of LOX to consume more Lac and alleviate tumor hypoxia to enhance the generation of singlet oxygen (O) upon light irradiation.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Key Laboratory for Special Functional Aggregate Materials of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong 250100, China.
The adsorption of DNA probes onto nanomaterials represents a promising bioassay technique, generally employing fluorescence or catalytic activity to generate signals. A significant challenge is maintaining the catalytic activity of chromogenic catalysts during detection while enhancing accuracy by overcoming the limitations of single-signal transmission. This article presents an innovative multimodal analysis approach that synergistically combines the oxidase-like activity of Fe-N-C nanozyme (Fe-NC) with red fluorescent carbon quantum dots (R-CQDs), further advancing the dual-mode analysis method utilizing R-CQDs@Fe-NC.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
School of Chemistry & Materials Science, Jiangsu Normal University, 101 Shanghai Road, Xuzhou 221116, P. R. China.
Long-term inflammation and persistent bacterial infection are primary contributors to unhealed chronic wounds. The use of conventional antibiotics often leads to bacteria drug resistance, diminishing wound healing effectiveness. Nanozymes have become a promising alternative to antimicrobial materials due to their low cost, easy synthesis, and good stability.
View Article and Find Full Text PDFACS Appl Bio Mater
January 2025
Collaborative Innovation Center of Tumor Marker Detection Technology, Equipment and Diagnosis Therapy Integration in Universities of Shandong, Shandong Province Key Laboratory of Detection Technology for Tumor Makers, College of Medicine, Linyi University, Linyi 276005, China.
The multiple enzymatic properties of the Au-modified metal-organic framework (Au-MOFs) have made it a functional catalytic system for antitumor treatment. However, in the face of insufficient catalytic substrates in tumor tissue, it is still impossible to achieve efficient treatment of tumors. Herein, Au-MOFs loaded with hyaluronic acid (HA)-modified calcium peroxide nanoparticles (CaO NPs) were used to construct a nanozyme (Au-MOF/CaO/HA) for substrate self-supplied and parallel catalytic/calcium-overload-mediated therapy of cancer.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!