Repellents play a major role in reducing the risk of mosquito-borne diseases by preventing mosquito bites. The present study evaluated the mosquito-repellent activity of β-caryophyllene oxide 1% (BCO), vetiver oil 2.5% (VO), and their binary mixtures (BCO + VO (1:1), BCO + VO (2:1), BCO + VO (1:2)) against four laboratory-colonized mosquito species, (L.), (Skuse), Theobald, and Say, using an excito-repellency assay system. In general, the compound mixtures produced a much stronger response in the mosquitoes than single compounds, regardless of the test conditions or species. The greatest synergetic effect was achieved with the combination of BCO + VO (1:2) in both contact and noncontact trials with (74.07-78.18%) and (55.36-83.64%). Knockdown responses to the binary mixture of BCO + VO were observed for , and , in the range of 18.18-33.33%. The synergistic repellent activity of BCO and VO used in this study may support increased opportunities to develop safer alternatives to synthetic repellents for personal protection against mosquitoes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532066 | PMC |
| http://dx.doi.org/10.3390/insects14090773 | DOI Listing |
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