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Cocaine-induced destruction of the palate: a diagnostic and management challenge.
Br Dent J
September 2024
Dublin Dental University Hospital, Trinity College Dublin, Ireland.
Article Synopsis
- * CIMDLs can be hard to diagnose because they resemble other conditions like infections or cancers, and they range from minor palatal perforations to severe sinonasal damage.
- * The report discusses four cases of CIMDLs treated at Dublin Dental University Hospital over a year and emphasizes the importance of awareness and a systematic approach for diagnosis and management.
Cocaine- and Levamisole-Induced Vasculitis: Defining the Spectrum of Autoimmune Manifestations.
J Clin Med
August 2024
Rheumatology Unit, Department of Medicine DIMED, University of Padua, 35128 Padua, Italy.
Article Synopsis
- Drug-induced vasculitis is a common type that mimics ANCA vasculitis, often linked to cocaine and levamisole use.
- These substances lead to various autoimmune conditions, including cocaine-induced midline destructive lesions and forms of vasculitis, creating a complex overlap in symptoms.
- The exact mechanisms of how cocaine causes these autoimmune issues remain unclear, complicating diagnosis and treatment, especially when there's no suspicion of drug abuse.
Orbital Complication in the Setting of Cocaine Use: A Case Report and Review of Literature.
Ophthalmic Plast Reconstr Surg
September 2024
McGovern Medical School, The University of Texas Health Science Center at Houston.
Orbital cellulitis is a common ophthalmologic consultation and has numerous risk factors; however, one that is seldomly encountered is chronic cocaine use. We describe a case of a 63-year-old man with a history of HIV and cocaine use who presented with OD pain, proptosis, and blurred vision. CT imaging revealed extensive erosions throughout the nasal septum, bilateral turbinates, ethmoid sinuses, and loss of the right medial orbital wall.
View Article and Find Full Text PDFCase Report: Toxic megacolon secondary to chronic constipation and cocaine consumption.
Front Surg
August 2024
Surgery Unit, Hospital General de México (HGM), Mexico City, Mexico.
Article Synopsis
- Toxic megacolon (TM) is a serious condition marked by extreme dilation of the colon, often linked to inflammatory bowel disease and infections.
- A unique case study describes a 25-year-old male with a history of recurrent constipation and cocaine use, who developed TM, requiring emergency surgery due to complications like intestinal obstruction and perforation.
- This case emphasizes the potential dangers of chronic constipation, particularly when combined with substance use, and the need for better understanding and monitoring of such patients’ medical histories.
Violaceous nodules of the extensor joints - a clinicopathological challenge.
Int J Dermatol
January 2025
Division of Dermatology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a condition characterized by vessel inflammation and may have a variety of etiologies. Among these, cocaine and its common adulterant, levamisole, have been described to contribute to the development of AAV with distinct cutaneous manifestations. Classically, these manifestations involve purpuric or necrotic lesions involving the ears, nose, and extremities.
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