AI Article Synopsis
- The study investigates the nutritional composition and health benefits of orange flesh sweet potato (OFSP) flour, which is a source of energy and beta-carotene.
- The research focuses on the flour’s antioxidant and immunomodulatory properties, particularly its impact on pro-inflammatory cytokines in murine macrophages.
- Findings reveal high levels of fiber, minerals, and polyphenols in OFSP flour, indicating potential for helping manage metabolic diseases linked to low-grade inflammation.
Article Abstract
Sweet potato (SP), Lam, belongs to the Convolvulaceae family. It produces edible storage roots. Currently, orange varieties contribute to improving food systems and managing vitamin A deficiency. Processing of this food crop into flour allows better conservation. However, nutrition health data regarding SP flour obtained by green extraction remains scarce. In this study, we therefore explored its phytochemistry and its associated bioactivity potential for human health. We analyzed the nutritional composition of orange flesh sweet potato (OFSP) flour and assessed the antioxidant (free radical scavenging) and immunomodulatory (on inflammatory murine macrophages) properties of the extract. More specifically, we measured the impact of OFSP flour extract on mediators such as Nitric Oxide (NO) and the production of pro-inflammatory cytokines such as Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha), Monocyte Chemoattractant Protein-1 (MCP-1), and Prostaglandin-E2 (PGE-2). Our results indicated significant fiber, mineral, beta-carotene, and polyphenols content in the extracts, and antioxidant and immunomodulatory bioactivities were also demonstrated with a concentration-dependent inhibition of cytokine production. Taken together, our results suggest that flour could, in addition to being a good source of energy and beta-carotene provitamin A, constitute a food of interest for the prophylaxis of metabolic diseases associated with an underlying low-grade inflammatory state.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529725 | PMC |
| http://dx.doi.org/10.3390/cimb45090440 | DOI Listing |
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