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| http://dx.doi.org/10.1002/acn3.51910 | DOI Listing |
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Order in Chaos: Lesser-Conserved and Repeat Structures in Dehydrins.
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January 2025
Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Dehydrins (Dhns) are a group of intrinsically disordered land plant proteins that are closely associated with tolerance of dehydrative stress. Dhns are recognized and classified by the presence and sequence of five different conserved segments, varying in length from 8 to 15 residues, separated by highly variable disordered regions. In addition to one or more copies of the diagnostic, fifteen-residue K segment, most Dhns can be classified into one of three major groups based on the mutually exclusive presence of three other conserved segments (H, Y, or F), with all three groups typically incorporating multi-serine S segments.
View Article and Find Full Text PDFBistable Functions and Signaling Motifs in Systems Chemistry: Taking the Next Step Toward Synthetic Cells.
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Department of Chemistry, Ben-Gurion University of the Negev, Be'er Sheva 84105, Israel.
ConspectusA key challenge in modern chemistry research is to mimic life-like functions using simple molecular networks and the integration of such networks into the first functional artificial cell. Central to this endeavor is the development of signaling elements that can regulate the cell function in time and space by producing entities of code with specific information to induce downstream activity. Such artificial signaling motifs can emerge in nonequilibrium systems, exhibiting complex dynamic behavior like bistability, multistability, oscillations, and chaos.
View Article and Find Full Text PDFProportions of incommensurate, resonant, and chaotic orbits for torus maps.
Chaos
January 2025
Department of Applied Mathematics, University of Colorado, Boulder, Colorado 80309-0526, USA.
This paper focuses on distinguishing classes of dynamical behavior for one- and two-dimensional torus maps, in particular, between orbits that are incommensurate, resonant, periodic, or chaotic. We first consider Arnold's circle map, for which there is a universal power law for the fraction of nonresonant orbits as a function of the amplitude of the nonlinearity. Our methods give a more precise calculation of the coefficients for this power law.
View Article and Find Full Text PDFDynamics of predator-prey system with the consequences of double Allee effect in prey population.
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Department of Mathematics, Vivekananda College, Thakurpukur, Kolkata, West Bengal, 700063, India.
A underlying complex dynamical behavior of double Allee effects in predator-prey system is studied in this article to understand the predator-prey relation more intensely from different aspects. We first propose a system with the Caputo sense fractional-order predator-prey system incorporating the Allee effect in prey populations to explain how the memory effect can change the different emergent states. Local stability analysis is analyzed by applying Matignon's condition for the FDE system.
View Article and Find Full Text PDFFrom chaos to order: optimizing fecal microbiota transplantation for enhanced immune checkpoint inhibitors efficacy.
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Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou, Guangdong, China.
The integration of fecal microbiota transplantation (FMT) with immune checkpoint inhibitors (ICIs) presents a promising approach for enhancing cancer treatment efficacy and overcoming therapeutic resistance. This review critically examines the controversial effects of FMT on ICIs outcomes and elucidates the underlying mechanisms. We investigate how FMT modulates gut microbiota composition, microbial metabolite profiles, and the tumor microenvironment, thereby influencing ICIs effectiveness.
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