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CKD-Associated Pruritus is Associated with Greater Use of Antidepressants and Anti-pruritus Medications.
Adv Ther
January 2025
CSL Vifor, Glattbrugg, Switzerland.
Introduction: Chronic kidney disease-associated pruritus (CKD-aP) is a common, yet underdiagnosed condition among patients on hemodialysis. Considering the lack of established treatment pathways, we sought to evaluate the use of antidepressant, systemic antihistamines, or gabapentinoid medications among patients with CKD-aP in the year following pruritus assessment.
Methods: We included 6209 patients on hemodialysis in the analysis.
Portuguese Society of Ophthalmology and Portuguese Society of Human Genetics Joint Clinical Practice Guidelines for Genetic Testing in Inherited Retinal Dystrophies.
Clin Genet
January 2025
Centro de Responsabilidade Integrado de Oftalmologia Pediátrica (CRI-OftaPed), Hospital Dona Estefânia, Unidade Saúde Local (ULS) São José, E.P.E., Lisboa, Portugal.
The Portuguese Society of Ophthalmology and the Portuguese Society of Human Genetics developed clinical practice guidelines to streamline genetic testing for inherited retinal dystrophies (IRDs), underlining the critical role of molecular diagnosis in enhancing patient care. Genetic testing is pivotal in diagnosis, genetic counselling, prognosis and access to clinical trials, and new gene-specific therapies. These guidelines recommend genetic testing in all IRD patients and provide a detailed assessment of available testing methods, ensuring that genetic counselling is integrated into ophthalmic care.
View Article and Find Full Text PDFGut microbiome and orthopaedic health: Bridging the divide between digestion and bone integrity.
World J Orthop
December 2024
Department of Orthopaedics, Brazilian Institute of Regenerative Medicine, Indaiatuba 13334-170, São Paulo, Brazil.
The gut microbiome, a complex ecosystem of microorganisms in the digestive tract, has emerged as a critical factor in human health, influencing metabolic, immune, and neurological functions. This review explores the connection between the gut microbiome and orthopedic health, examining how gut microbes impact bone density, joint integrity, and skeletal health. It highlights mechanisms linking gut dysbiosis to inflammation in conditions such as rheumatoid arthritis and osteoarthritis, suggesting microbiome modulation as a potential therapeutic strategy.
View Article and Find Full Text PDFThree-Dimensional Sectional Measurements of Shoulder Muscle Volume and Computed Tomography Density to Monitor Serial Postoperative Volume Changes in the Transverse Force Couple of Shoulder Muscles in Anterior Shoulder Instability.
Cureus
December 2024
Radiology, Saitama Medical University, Saitama, JPN.
Purpose: In this study, we evaluated serial changes in shoulder muscle volume and computed tomography (CT) density of the transverse force couple (i.e., subscapularis (Ssc) vs.
View Article and Find Full Text PDFSex workers and their stories: using timelines as a creative method in research involving underserved populations.
Nurse Res
January 2025
Reader in health promotion, Leeds Beckett University, Leeds, England.
Background: Researchers may often find it challenging to gather data with underserved populations, even when using traditional qualitative methods. They may also be at risk of further entrenching the hegemony of the dominant narrative, silencing participants' experiences and further marginalising and excluding those most in need. Timelines and other creative methods are useful, sensitive tools that combine flexibility and malleability with an ethical appeal, such as feminist ethics of care.
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